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Home oxygen use unrelated to readmission risk in preemies with bronchopulmonary dysplasia

05 May 2020

Home use of oxygen does not appear to amplify the risk of readmission for preterm infants with bronchopulmonary dysplasia (BPD), a recent study has shown.

The study included 3,574 preterm infants born <32 weeks of gestation. All participants had been diagnosed with BPD, and those with anomalies or tracheostomies were excluded. The primary outcome of interest was readmission by 1 year of corrected age. Readmission duration and mortality were set as secondary outcomes.

More than half of the participants were discharged with home oxygen and 34 percent (n=1,223) needed to be readmitted to a hospital by 1 year of corrected age. Factors associated with readmission included earlier gestational age, more ventilator days, BPD severity, patent ductus arteriosus ligation and having a gastrostomy tube, among others.

Multivariable analysis found that while home oxygen use was a potential risk factor for readmission, it failed to reach statistical significance (odds ratio [OR], 1.2, 95 percent confidence interval [CI], 0.98–1.56; p=0.074). It was also unrelated to the secondary outcome of total readmission days (OR, 1.0, 95 percent CI, 0.82–1.18; p=0.871).

“Despite significant variation across children’s hospitals in the use of home oxygen, we found no association between center use of home oxygen and readmission risk; however, readmissions for infants discharged with home oxygen were more likely to be coded as BPD without differences in other respiratory, infectious or cardiovascular codes,” researchers said.

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Most Read Articles
6 days ago
Chest pain appears to be the principal complaint of patients hospitalized with a first myocardial infarction (MI), particularly among those in the youngest age group, a study has found.
Jairia Dela Cruz, 16 Sep 2020
In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.
Pearl Toh, 6 days ago
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
20 Sep 2020
Women with pre-eclampsia are at higher risk of developing heart failure, a study suggests.