Most Read Articles
12 May 2016

A study published in Science shows new strains of microbes from the donor were more likely to colonize the patient’s intestines if that particular species exists in the patient’s gut.

Rachel Soon, 18 Jan 2017

Patients infected with Helicobacter pylori strains derived from different geographical human ancestries than their own are likely to develop more severe symptoms which include gastric cancers, says an expert.

Jairia Dela Cruz, 19 Oct 2017
Having both type 1 diabetes and coeliac disease (CD) autoimmunity in early childhood appears to be more common than expected, with the development of islet autoantibodies (IAs) conferring a significant risk of subsequent tissue transglutaminase autoantibodies (tTGAs), according to data from the TEDDY* study.
Pank Jit Sin, 27 Dec 2017
The addition of synbiotics to the diet of adults suffering from functional constipation may lead to significant improvement in constipation syndroms. 

Home-based exercise improves aerobic power in cirrhosis patients

17 Jan 2018

In patients with cirrhosis, 8 weeks of a home-based exercise training (HET) regimen effectively improves exercise capacity, peak aerobic power (peak VO2) and 6-minute walk distance (6MWD), particularly in those with high adherence, a recent study has shown.

Researchers randomized 40 participants (mean age 57 years; 58 percent male) to receive either 8 weeks of HET, comprised of moderate-to-high‒intensity cycling 3 days/week, or usual care. Peak VO2 showed significant improvement from baseline in the HET group (1.44±0.40 to 1.57±0.56 L/min; p=0.04) but not in the control group (1.87±0.66 to 1.87±0.70 L/min; p=0.98).

The changes in peak VO2 were statistically comparable between the two groups (mean change, 0.15; 95 percent CI, ‒0.03 to 0.32; p=0.095).

In terms of secondary outcomes, there was a statistically significant improvement in aerobic endurance in the 6MWD test in favour the HET group (mean change, 33.7 m; 5.1–62.4; p=0.02). Significant improvements in thigh circumference (p=0.02) and thigh muscle thickness (p=0.05) were also observed in the HET group alone.

Categorizing the HET participants according to adherence produced two groups of almost equal size: those who completed 80 percent of the sessions (adherers; 55 percent; n=11) and those who completed less (nonadherers; 45 percent; n=9).

Subsequent analyses showed that improvements were more pronounced and significant in adherers. Peak VO2 increased from 18.5±4.5 at baseline to 21.4±6.7 mL/kg/min at study end (p=0.01) while the 6MWD improved from 503.6±96.3 to 534.0±102.7 m (p=0.003).

HET did not significantly affect quality of life relative to usual care, and no adverse events were recorded.

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Most Read Articles
12 May 2016

A study published in Science shows new strains of microbes from the donor were more likely to colonize the patient’s intestines if that particular species exists in the patient’s gut.

Rachel Soon, 18 Jan 2017

Patients infected with Helicobacter pylori strains derived from different geographical human ancestries than their own are likely to develop more severe symptoms which include gastric cancers, says an expert.

Jairia Dela Cruz, 19 Oct 2017
Having both type 1 diabetes and coeliac disease (CD) autoimmunity in early childhood appears to be more common than expected, with the development of islet autoantibodies (IAs) conferring a significant risk of subsequent tissue transglutaminase autoantibodies (tTGAs), according to data from the TEDDY* study.
Pank Jit Sin, 27 Dec 2017
The addition of synbiotics to the diet of adults suffering from functional constipation may lead to significant improvement in constipation syndroms.