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Roshini Claire Anthony, 2 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 5 days ago
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
Jairia Dela Cruz, 6 days ago
Male smokers under the age of 50 years are at risk of developing ischaemic stroke, and this risk increases with the number of cigarettes smoked daily, according to data from the Stroke Prevention in Young Men Study.
Yesterday
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Home-based dialysis tied to reduced health deterioration in elderly patients

17 Sep 2017

Home-based dialysis, regardless of type, appears to reduce the risk of worsening health in older patients, according to a prospective longitudinal cohort study from New Zealand.

Researchers performed a modified Poisson regression analysis to determine the predictors of worse health status in a cohort 150 elderly patients (aged ≥65 years) receiving long-term dialysis. Patient-reported social and health characteristics were evaluated using the 36-Item Short Form Health Survey, EQ-5D and Kidney Symptom Score questionnaires, and clinical information from health records.

The main outcome was health status after 12 months of follow-up, and results showed that 35 percent of the cohort reported worse health or had died at 12 months.

Baseline variables independently associated with reduced risk of worse health status included Pacific ethnicity (relative risk [RR], 0.63; 95 percent CI, 0.53 to 0.72), greater bother on the Kidney Symptom Score (RR, 0.78; 0.62 to 0.97) and dialysis at home (haemodialysis: RR, 0.55; 0.36 to 0.83; peritoneal dialysis: RR, 0.86; 0.79 to 0.93).

On the other hand, baseline variables independently associated with increased risk of worse health status included greater social dissatisfaction (RR, 1.66; 1.27 to 2.17), lower sense of community (RR, 1.70; 1.09 to 2.64), comorbid conditions (RR, 1.70; 1.09 to 2.64), EQ-5D anxiety/depression (RR, 1.61; 1.07 to 2.42), poor/fair overall general health (RR, 1.60; 1.37 to 1.85) and longer dialysis therapy duration (RR, 1.03; 1.00 to 1.05).

Despite the small sample size and restricted study power, the present data should provide encouragement to home-dialyzing patients and their clinicians alike, researchers said.

“Should this finding be confirmed in other countries, this may lead to increased consideration by clinicians and policy makers of more patient-centred home-based dialysis treatment options for older patients with end-stage kidney disease,” they added.

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Most Read Articles
Roshini Claire Anthony, 2 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 5 days ago
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
Jairia Dela Cruz, 6 days ago
Male smokers under the age of 50 years are at risk of developing ischaemic stroke, and this risk increases with the number of cigarettes smoked daily, according to data from the Stroke Prevention in Young Men Study.
Yesterday
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.