Most Read Articles
Rachel Soon, 14 Mar 2020

SARS-CoV-2 may remain in aerosols over 3 hours after exposure, and on surfaces up to 3 days, making it similar to SARS-CoV-1 in environmental stability, according to a new study.

Roshini Claire Anthony, 18 Mar 2020

Vaccination against herpes zoster (shingles) with the Zoster Vaccine Live (ZVL) vaccine may reduce the risk of stroke in older adults, according to a study presented at the recent ISC 2020 conference.

07 Feb 2020
The risk of developing bronchopulmonary dysplasia (BPD) appears to be twofold higher in neonates exposed to ibuprofen during the first days of life, a study has found.

Product Highlight - Benlysta

20 Dec 2019
Adding BENLYSTA to standard therapy:
• Superior reduction in SLE disease activity1*†‡
• Reduction in corticosteroid dose in patients on >7.5 mg/day at baseline1#
• Severe flare risk reduction by 50%1
• Significant improvement in fatigue as early as Week 82^
• Rates of adverse events were similar between BENLYSTA and placebo1-3*

Remarks: * Defined as positive anti-dsDNA (≥30 IU/mL) and low C3 and/or C4 complement. Standard therapies permitted, alone or in combination: corticosteroids, immunosuppressants, antimalarials, and NSAIDs. BLISS-52 and BLISS-76 pooled data. # Reduction to ≤7.5 mg/day: 24.6% vs 15.0% (p = 0.035).
^ FACIT-Fatigue score improvement at Week 52: 4.07 vs 1.80 (p = 0.004).

References:
1. Benlysta SC Prescribing Information version GDS15.
2. van Vollenhoven RF, Petri MA, Cervera R, et al. Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response. Ann Rheum Dis. 2012;71:1343-1349.
3. Navarra SV, Guzman RM, Gallacher AE, et al. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial. Lancet. 2011;377(9767):721-731.


Related MIMS Drugs

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Pharmacy - Hong Kong digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Rachel Soon, 14 Mar 2020

SARS-CoV-2 may remain in aerosols over 3 hours after exposure, and on surfaces up to 3 days, making it similar to SARS-CoV-1 in environmental stability, according to a new study.

Roshini Claire Anthony, 18 Mar 2020

Vaccination against herpes zoster (shingles) with the Zoster Vaccine Live (ZVL) vaccine may reduce the risk of stroke in older adults, according to a study presented at the recent ISC 2020 conference.

07 Feb 2020
The risk of developing bronchopulmonary dysplasia (BPD) appears to be twofold higher in neonates exposed to ibuprofen during the first days of life, a study has found.