Most Read Articles
Dr. Joseph Delano Fule Robles, 14 Nov 2017

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

14 Nov 2017
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
6 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.

Higher serum albumin level after PEG tube insertion predicts longer survival

16 Mar 2017

Survival after percutaneous endoscopic gastrostomy (PEG) tube insertion in elderly patients with severe dementia is potentially influenced by a higher serum albumin level at baseline and a stable/increased serum albumin level during follow-up, suggest a recent study.

Researchers enrolled 189 patients (aged ≥64 years) with severe dementia who underwent PEG tube insertion from 2002 to 2011 at a tertiary hospital and followed through 2014 to determine the factors affecting survival after such procedure. They collected data on background diseases, laboratory tests conducted 14 days before and 90 days after PEG, and date of death.

Multivariate Cox regression analysis was performed and cumulative survival curves plotted.

Patients who died ≤30 days after PEG (n=32; 16.9 percent) had significantly lower mean baseline serum albumin level than those who survived longer (2.9 vs 3.3 g/dL; p<0.001). Also, patients who survived 1 year after PEG (n=96; 50.8 percent) had significantly higher serum albumin level than those who died earlier (3.4 vs 3.1 g/dL; p=0.002). There were no significant differences in other laboratory parameters.

A serum albumin level above the median (3.3 g/dL) was the sole predictor of survival after adjustment for background diseases (hazard ratio [HR], 0.51; 95 percent CI, 0.37 to 0.72; p<0.001). A stable/increased serum albumin levels at 90 days after PEG resulted in longer survival in patients, compared with decreased levels.

After adjustment for age and background diseases, the only predictor of survival was a stable/increased albumin level at 90 days (HR, 0.59; 0.42 to 0.85; p=0.004).

These findings support a previous study which concluded the potential of serum albumin to predict early survival in individuals undergoing PEG tube placement. [JPEN J Parenter Enteral Nutr 1997;21:72-4]

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Most Read Articles
Dr. Joseph Delano Fule Robles, 14 Nov 2017

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

14 Nov 2017
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
Both hatha yoga and a low-FODMAP (Fermentable, Oligo-, Di-, Monosaccharides and Polyol) diet can alleviate gastrointestinal symptoms, as well as improve a range of other psychological and physiological health parameters, in patients with irritable bowel syndrome (IBS), a study has shown.
6 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.