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Higher dairy milk intake may promote breast cancer

15 Apr 2020

Consuming high amounts of dairy milk and calories from dairy appears to contribute to an increased risk of developing breast cancer, a study has found.

Researchers followed 52,795 women (mean age, 57.1 years), who were initially free of cancer, for 7.9 years. They estimated dietary intakes from food frequency questionnaires, as well as from six structured 24-h dietary recalls in 1,011 women included in the calibration study. Incident invasive breast cancers were identified through cancer registry linkage.

There were 1,057 new breast cancer cases documented during follow-up. Multivariable proportional hazards regression models showed no clear associations between soy products and breast cancer, independently of dairy.

However, 90th vs 10th percentiles of intakes of dairy calories and dairy milk were associated with a risk increase. The respective hazard ratios (HRs) were 1.22 (95 percent confidence interval [CI], 1.05–1.40) and 1.50 (95 percent CI, 1.22–1.84). Results were similar for full fat and reduced fat milks, whereas no significant relationships were noted for cheese and yogurt.

When median intakes of dairy milk were replaced with soy milk, the risk of breast cancer was attenuated (HR, 0.68, 95 percent CI, 0.55–0.85).

Similar-sized associations were noted among pre- and postmenopausal breast cancer cases, with CIs also excluding the null in oestrogen receptor (ER+, ER–) and progesterone receptor (PR+) cancers.

In light of the findings, researchers pointed out that current guidelines for dairy milk consumption should be viewed with some caution.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 3 days ago
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.
3 days ago
Use of thyroid hormone therapy does not seem to protect older adults with subclinical hypothyroidism against mortality, but it appears to confer survival benefits to those aged <65 years, results of a study have shown.