Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

High vegetable protein intake lowers risk of early menopause

28 Jul 2017

Increased consumption levels of protein from vegetable sources, equivalent to three to four servings per day of protein-rich foods, is associated with lower incidence of early onset of natural menopause, a US study suggests.

Researchers examined 85,682 women participating in the Nurses’ Health Study II cohort who were premenopausal at baseline (1991) and followed until 2011 for onset of natural menopause. Protein intake was measured using the food frequency questionnaire.

During the study period, menopause occurred early in 2,041 women. In Cox proportional hazard models, the highest quintile of vegetable protein intake (median, 6.5 percent of calories) significantly lowered the risk of early menopause by 16 percent compared with the lowest quintile of intake (median, 3.9 percent of calories; hazard ratio [HR], 0.84; 95 percent CI, 0.73 to 0.98; p=0.02).

Each 1 percent increase in vegetable protein intake was associated with a significant 6-percent reduction in the risk of early menopause. Consumption of specific foods including pasta, dark bread and cold cereal was similarly associated with a lower risk (p<0.05). In contrast, animal protein intake was not found to be related to the risk of early menopause.

Early menopause involves the cessation of ovarian function <45 years. This event occurs in about 5 to 10 percent of Western women and ups the risk of adverse health outcomes, such as premature mortality and cardiovascular disease. [Endocrinology Metabolism Clinics of North America 2015;44:543-557; Endocrine Rev 2009;30:465-493]

Moreover, women with early menopause may have reduced fertility as much as a decade prior to onset of menopause. The factors associated with natural early menopause are not well understood, and the majority of diagnoses are not attributable to genetic factors or autoimmune conditions. [Maturitas 2010;65:161-166]

Researchers said additional prospective studies are needed to investigate the potential mechanisms involved in the effect of soy- and nonsoy-based vegetable proteins on the onset of menopause.

“A better understanding of how dietary vegetable protein intake is associated with ovarian ageing may identify ways for women to modify their risk of early onset of menopause and associated health conditions,” they added.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.