Most Read Articles
Roshini Claire Anthony, 5 days ago

Children who are fully vaccinated against the flu, ie, receive the recommended number of influenza vaccine doses, have a lower risk of acquiring influenza compared with those who are partially vaccinated, a US study found.

06 Jul 2020
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Yesterday
Treatment with levothyroxine appears to have no significant impact on systolic and diastolic heart function in older adults with mild subclinical hypothyroidism as compared with placebo, results of a study have shown.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.

High myopia modifies OCT measurements

16 Jun 2020

Optical coherence tomography (OCT) measurements are altered in patients with high myopia, a recent study has found.

The study included 92 high myopia patients (mean age, 35.19±14.29 years; 56 females) who contributed 92 eyes for analysis. OCT was performed to measure the thickness of the retinal nerve fibre layer (RNFL) and of the superior and inferior ganglion cell complex (GCC). A parallel group of 70 eyes from 70 controls (mean age, 36.22±11.42 years; 42 females) was also included.

Compared to controls, patients with high myopia had significantly thinner superior and inferior GCC measurements (p<0.001). RNFL thickness at the superior, inferior, and nasal regions, as well as scores in the Early Treatment Diabetic Retinopathy Study (ETDRS) tool, were likewise significantly different between groups (p<0.001). Central macular thickness did not differ between groups.

Moreover, the superficial (SVD; p=0.005) and deep (DVD; p<0.001) vascular densities were significantly reduced in patients with high myopia.

Researchers then found that both SVD and DVD were negatively associated with axial length (AL). In contrast, GCC, RNFL, and best-corrected visual acuity were all significant and positive correlates.

Multivariate regression analysis additionally showed that in high myopia patients, high SVD was independently associated with shorter AL and greater mean RNFL thickness. DVD, on the other hand, correlated with better visual acuity and shorter AL.

“Vascular alterations may be one of the main pathophysiological mechanisms in high myopia, and alternative treatments and preventive measures targeting these vascular alterations may be the subject of future studies,” researchers said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 5 days ago

Children who are fully vaccinated against the flu, ie, receive the recommended number of influenza vaccine doses, have a lower risk of acquiring influenza compared with those who are partially vaccinated, a US study found.

06 Jul 2020
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Yesterday
Treatment with levothyroxine appears to have no significant impact on systolic and diastolic heart function in older adults with mild subclinical hypothyroidism as compared with placebo, results of a study have shown.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.