Most Read Articles
Roshini Claire Anthony, 11 Feb 2020

The consumption of processed meat or unprocessed red meat may be associated with a slightly elevated risk of incident cardiovascular disease (CVD)* and all-cause mortality, according to a US study.

29 Jan 2020
Several high-density lipoprotein (HDL) functionality parameters, which are linked to HDL roles on cholesterol metabolism, endothelial protection and antioxidant/anti-inflammatory defence, contribute to an increased risk of incident acute coronary syndromes and its manifestations in individuals at high risk of cardiovascular disease, a study reports.
Jairia Dela Cruz, 6 days ago
A wearable arrhythmia detection device, the AliveCor KardiaBand (KB), demonstrates moderate accuracy for diagnosing atrial fibrillation (AF) in comparison with a 12-lead electrocardiogram (ECG), as shown in a recent study. However, combining the automated device diagnosis with the electrophysiologists (EP) interpretation of unclassified readings improves overall accuracy.
Pearl Toh, 10 Feb 2020
Contrary to popular concern, use of statins was not associated with a greater decline in memory or cognition in the elderly over 6 years, according to data from the observational MAS*.

High incidence of serious adverse events seen during transcatheter pulmonary valve replacement

30 Jan 2020

Analysis of a large-scale registry data reveals a high incidence of serious adverse events (SAE) during transcatheter pulmonary valve replacement (TPVR). Mortality, however, is not common.

In addition, radiation dose is greater than for other congenital interventions and is associated with patient and procedural factors. Reintervention is common during early follow-up.

The investigators accessed the multicentre C3PO-QI registry and identified patients who underwent TPVR from 1 January 2014 to 31 December 2016. SAE referred to the occurrence of 1 moderate, major or catastrophic events. Radiation dose was reported as dose area product adjusted for weight. Univariate and multivariate analyses were performed to explore associations with outcome measures.

TPVR was carried out in 530 patients (median age, 18.3 years; median weight, 58 kg; 59 percent male) at 14 centres. Implant substrate included homograft (41 percent), bioprosthesis (30 percent), native right ventricular outflow tract (RVOT; 27 percent) and other (2 percent). The most common TPVR indication was mixed (49 percent), followed by pulmonary insufficiency (28 percent) and stenosis (23 percent).

AE occurred in 26 percent of patients and SAE in 13 percent, including 1 death. SAEs more frequently occurred in homograft conduit than other RVOT substrates, but SAE type and severity differed between implant substrates.

Median radiation dose was 198 μGy·m2/kg, and a higher dose was found to be associated with older age, greater RVOT obstruction and concomitant interventions (p<0.001).

Furthermore, 13.3 percent underwent surgery, catheterization or both, unrelated to infection, during a median follow-up of 1 year. TPV reintervention correlated with younger age, smaller size, and haemodynamic and anatomic factors indicative of greater RVOT obstruction.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 11 Feb 2020

The consumption of processed meat or unprocessed red meat may be associated with a slightly elevated risk of incident cardiovascular disease (CVD)* and all-cause mortality, according to a US study.

29 Jan 2020
Several high-density lipoprotein (HDL) functionality parameters, which are linked to HDL roles on cholesterol metabolism, endothelial protection and antioxidant/anti-inflammatory defence, contribute to an increased risk of incident acute coronary syndromes and its manifestations in individuals at high risk of cardiovascular disease, a study reports.
Jairia Dela Cruz, 6 days ago
A wearable arrhythmia detection device, the AliveCor KardiaBand (KB), demonstrates moderate accuracy for diagnosing atrial fibrillation (AF) in comparison with a 12-lead electrocardiogram (ECG), as shown in a recent study. However, combining the automated device diagnosis with the electrophysiologists (EP) interpretation of unclassified readings improves overall accuracy.
Pearl Toh, 10 Feb 2020
Contrary to popular concern, use of statins was not associated with a greater decline in memory or cognition in the elderly over 6 years, according to data from the observational MAS*.