Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
2 days ago
Daily intake of cow’s milk formula in early life helps prevent the development of cow’s milk allergy later on without competing with breastfeeding, a recent study has found.

High dietary nicotine intake lowers risk of Parkinson disease in women

12 Oct 2020

Greater consumption of dietary nicotine reduces the risk of Parkinson’s disease (PD) in women, results of a study have shown.

This study was based on never-smoker participants from two large prospective cohorts: the Nurses’ Health Study (n=31,615) and the Health Professionals Follow-up Study (n=19,523). These cohorts had available information on dietary nicotine intake from 1986 from validate food frequency questionnaires.

The investigators calculated dietary nicotine based on consumption of peppers, tomatoes, processed tomatoes, potatoes, and tea. Questionnaires were utilized to identify incident PD cases, which were subsequently confirmed by reviewing medical records. Cohort-specific hazard ratios (HRs) and pooled HR were calculated using Cox proportional hazard models and fixed-effects models, respectively.

A total of 601 incident PD cases (305 men and 296 women) were identified during 26 years of follow-up. The pooled HR after adjusting for potential covariates was 0.70 (95 percent confidence interval [CI], 0.51–0.94) for the highest vs lowest quintile of dietary nicotine intake. However, the inverse association was only observed in women (adjusted HR, 0.64, 95 percent CI, 0.42_0.96), not in men (adjusted HR, 0.77, 95 percent CI, 0.50–1.20).

Similar significant results in women were observed after further adjustments for environmental tobacco smoke exposure, family history of PD, and use of ibuprofen.

Notably, high peppers intake correlated with a lower risk of PD (adjusted HR for ≥5 times/week compared with ≤3 times/month, 0.49, 95 percent CI, 0.25–0.94) in women but not in men (adjusted HR, 1.04, 95 percent CI, 0.57–1.90).

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
2 days ago
Daily intake of cow’s milk formula in early life helps prevent the development of cow’s milk allergy later on without competing with breastfeeding, a recent study has found.