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Pearl Toh, 6 days ago
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This study validated the effect of subglottic secretion suctioning on ventilator-associated pneumonia prevalence and to gauge its associated impact on ventilator-associated conditions and antibiotic use.

High BMI protects against risk of lung cancer mortality

24 Sep 2017
Lack of public awareness about the way lung cancer strikes is a big factor in delaying diagnosis and treatment

There is a nonlinear association between body mass index (BMI) and risk of lung cancer mortality, where individuals with higher BMI have less risk of death, according to a recent meta-analysis.

Among the 15 studies (n=15,191,571) eligible for inclusion, 28,273 deaths from lung cancer were reported. For every 5 kg/m2 increase in BMI, a pooled relative risk (RR) of 0.94 (95 percent CI, 0.92 to 0.96; p=0.000) for lung cancer mortality risk was calculated.

There was a significant nonlinear association between the risk of death from lung cancer and BMI (p<0.0001 for nonlinearity), such that those with lower BMI had higher risks of mortality from lung cancer.

Because of considerable heterogeneity, subgroup analyses were performed and showed that females benefited from high BMI more than males, as did smokers than nonsmokers.

The current meta-analysis involved studies that focused on the effect of BMI on the risk of mortality from lung cancer. The databases of Pubmed and Embase were accessed.

Of the 15 studies eligible, five were conducted in Europe, six in America and four in Asia. Sample size varied and ranged from 2,054 to 1,200,000 patients. All but one report were population-based studies. The total study duration lasted for more than 200 million person-years.

In terms of quality, seven of the 15 studies had high quality, according to the Newcastle-Ottawa scale. The remaining eight studies had moderate quality. The Egger and Begg tests showed that there was no evidence of publication bias.

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Most Read Articles
Pearl Toh, 6 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
Stephen Padilla, 09 Jan 2018
Very elderly adults have the highest rate of invasive pneumococcal diseases, according to a recent study, suggesting that age influences manifestations of this illness.
27 Dec 2017
The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.
23 Oct 2014
This study validated the effect of subglottic secretion suctioning on ventilator-associated pneumonia prevalence and to gauge its associated impact on ventilator-associated conditions and antibiotic use.