Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 5 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.
6 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.

High animal protein intake ups risk of incident kidney stones

18 Nov 2019
Spread your protein consumption out to ensure you are getting a sufficient and healthy intake.

Higher consumption of animal protein appears to increase the risk of developing kidney stones, according to a study involving a population with a relatively low animal protein intake and a high plant protein intake in Shanghai, China. Increasing the proportion of plant relative to animal protein may protect against this risk.

Overall, 1,451 men and 1,202 women reported incident stones during 319,211 and 696,950 person-years of follow-up. The average consumption per day of animal and plant protein standardized to 2,000 kcal was 31.3±13.7 and 48.4±7.2 gm in women and 30.8±13.3 and 51.3±7.6 gm in men, respectively.

Multivariable analysis revealed an increased risk of incident stones among participants in the highest quintiles of animal and nondairy animal protein intake compared to those in the lowest quintiles (hazard ratio [HR], 1.16, 95 percent confidence interval [CI], 1.01–1.32; p=0.03 vs HR, 1.14, 95 percent CI, 1.01–1.30; p=0.04).

The highest intake quintiles of animal-to-plant protein ratios (HR, 1.17, 95 percent CI, 1.03–1.33; p=0.02) and nondairy animal-to-plant protein ratios (HR, 1.20, 95 percent CI, 1.06–1.36; p=0.005) positively correlated with stone risk compared to the lowest quintile. Association with plant protein intake (p-trend=0.14) was not observed.

This study obtained dietary intakes from a validated food frequency questionnaire at baseline. Self-reported stone events were ascertained at baseline and at follow-up visits. The associations between protein intake and incident stone risk were assessed using multivariable Cox regression models.

“High animal protein intake is a risk factor for nephrolithiasis,” the authors noted.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 5 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.
6 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.