Most Read Articles
2 days ago
The use of capsule endoscopy (CE) appears to be effective in the diagnosis of iron deficiency anaemia (IDA), yielding a 33.9-percent yield in this study, with 65.8 percent of patients undergoing further workup and 12.7 percent requiring therapeutic intervention.
Tristan Manalac, Yesterday
Minimally invasive pancreatectomy (MIP) offers a feasible alternative to open pancreatectomy (OP) for the treatment of pancreatic neuroendocrine neoplasms (PNEN), according to a recent Singapore study has found.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.

Herpes simplex virus contributes to infertility in men

13 Jan 2018

In male partners of infertile couples, infection with herpes simplex virus (HSV) appears to exert a negative effect on two equally important components of semen, spermatozoa and seminal fluid, which may in turn influence fertility, as shown in a recent study.

Researchers examined a total of 279 semen samples from males aged ≥18 years. All men had a semen analysis due to fertility evaluation following a failure to conceive with their partner after 1 year of unprotected intercourse.

Basic seminal parameters were analysed, with HSV infection detected by multiplex polymerase chain reaction (M-PCR) assay.

M-PCR assay detected HSV in 10.7 percent of samples, of which 7.5 percent had HSV-1 exclusively and 3.2 percent had HSV-2 exclusively.

There were significant associations observed between HSV-2 infection and hematospermia and a lower mean seminal volume, and between HSV-1 infection and a lower mean sperm count.

“Further studies enrolling a larger number of patients are necessary to confirm [the present] data and to elucidate the clinical relevance of HSV presence in semen,” researchers said.

HSV-1 causes oral and occasionally genital cold sores, whereas HSV-2 is the most common cause of genital herpes. The effect of HSV on infertility may be caused by epididymal and prostatic function, as indicated by reduced concentrations of neutral α­glucosidase and citrate in HSV-positive semen samples. Notably, it has been shown that antiviral treatment (acyclovir and valacyclovir) can help HSV-positive, infertile male patients achieve pregnancy. [Nat Rev Urol 2014;11:672-687]

Editor's Recommendations
Most Read Articles
2 days ago
The use of capsule endoscopy (CE) appears to be effective in the diagnosis of iron deficiency anaemia (IDA), yielding a 33.9-percent yield in this study, with 65.8 percent of patients undergoing further workup and 12.7 percent requiring therapeutic intervention.
Tristan Manalac, Yesterday
Minimally invasive pancreatectomy (MIP) offers a feasible alternative to open pancreatectomy (OP) for the treatment of pancreatic neuroendocrine neoplasms (PNEN), according to a recent Singapore study has found.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.