Most Read Articles
Pearl Toh, 3 days ago
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
26 Dec 2017
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
24 Aug 2016

Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.

Rachel Soon, 12 Dec 2018

MIMS Pharmacist presents an overview of superoxide dismutase (SOD) and its role in resisting the effects of oxidative stress and aging.

Hepatitis C presents increased risk of metabolic syndrome

03 Oct 2018

It appears that the risk of metabolic syndrome (MetS) is heightened in the presence of hepatitis C virus (HCV) infection but is reduced only in lean patients with hepatitis B virus (HBV) infection, a study has found.

The study included 180,359 individuals aged 40 years who underwent a series of community‐based health screenings. Of these, 18,726 (10.4 percent) had HBV, 13,428 (7.4 percent) had HCV and 1,337 (0.7 percent) had HBV plus HCV (B+C). The remaining 146,868 (81.5 percent) were non‐HBV/non‐HCV controls (NBNC).

MetS had a prevalence rate of 30.1 percent overall. For the subgroups, prevalence rates were 25.2 percent in patients with HBV, 31.5 percent in those with HCV, 28.9 percent in those with B+C and 30.7 percent in NBNC controls (p<0.001).

Among 54,361 individuals with MetS, body mass index status was lean in 18.8 percent, overweight in 35.4 percent and obese in 45.8 percent. Compared with obese individuals with MetS, their lean counterparts were older, had more diabetes and had higher metabolic component levels, but had lower alanine transaminase and aspartate transaminase‐platelet ratio index levels.

Logistic regression analysis showed a significant, positive association between HCV infection and MetS (p<0.001). On the other hand, HBV infection was inversely associated with MetS only among lean individuals (p=0.002) but not among the general population.

Researchers pointed out that older age and female gender are the two most important factors contributing to an increased risk of MetS, which is highly prevalent in postmenopausal women.

Additionally, the current study demonstrates that lean MetS, similar to lean nonalcoholic fatty liver disease, may exhibit more manifestations of extrahepatic diseases but not increase the risk of hepatic severity compared with obese MetS, they said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Pharmacist - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 3 days ago
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
26 Dec 2017
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
24 Aug 2016

Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.

Rachel Soon, 12 Dec 2018

MIMS Pharmacist presents an overview of superoxide dismutase (SOD) and its role in resisting the effects of oxidative stress and aging.