Most Read Articles
Pearl Toh, 6 days ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
Rachel Soon, 05 Dec 2018

At the recent Malaysian Community Pharmacy Business Forum (MyCPBF), a discussion forum was held on the subject of “Transcending Primary Healthcare Services: The Future of Specialized Pharmacy Services and Pharmacy Specialization”.

Dr Renly Lim, 01 Aug 2018
Palliative care uses an integrated, multidisciplinary approach to reduce suffering and to improve the quality of life of patients battling with life-threatening illnesses.
29 Jan 2017
The over-the-counter cough medicine CS1002 does not appear to induce a significant improvement in cough severity, although it may produce greater reductions in cough frequency and sleep disruption compared with simple linctus (SL), according to a study. Furthermore, the drug is associated with increased resolution of cough, resulting in early treatment discontinuation and improved health status.

Hepatitis C presents increased risk of metabolic syndrome

03 Oct 2018

It appears that the risk of metabolic syndrome (MetS) is heightened in the presence of hepatitis C virus (HCV) infection but is reduced only in lean patients with hepatitis B virus (HBV) infection, a study has found.

The study included 180,359 individuals aged 40 years who underwent a series of community‐based health screenings. Of these, 18,726 (10.4 percent) had HBV, 13,428 (7.4 percent) had HCV and 1,337 (0.7 percent) had HBV plus HCV (B+C). The remaining 146,868 (81.5 percent) were non‐HBV/non‐HCV controls (NBNC).

MetS had a prevalence rate of 30.1 percent overall. For the subgroups, prevalence rates were 25.2 percent in patients with HBV, 31.5 percent in those with HCV, 28.9 percent in those with B+C and 30.7 percent in NBNC controls (p<0.001).

Among 54,361 individuals with MetS, body mass index status was lean in 18.8 percent, overweight in 35.4 percent and obese in 45.8 percent. Compared with obese individuals with MetS, their lean counterparts were older, had more diabetes and had higher metabolic component levels, but had lower alanine transaminase and aspartate transaminase‐platelet ratio index levels.

Logistic regression analysis showed a significant, positive association between HCV infection and MetS (p<0.001). On the other hand, HBV infection was inversely associated with MetS only among lean individuals (p=0.002) but not among the general population.

Researchers pointed out that older age and female gender are the two most important factors contributing to an increased risk of MetS, which is highly prevalent in postmenopausal women.

Additionally, the current study demonstrates that lean MetS, similar to lean nonalcoholic fatty liver disease, may exhibit more manifestations of extrahepatic diseases but not increase the risk of hepatic severity compared with obese MetS, they said.

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Most Read Articles
Pearl Toh, 6 days ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
Rachel Soon, 05 Dec 2018

At the recent Malaysian Community Pharmacy Business Forum (MyCPBF), a discussion forum was held on the subject of “Transcending Primary Healthcare Services: The Future of Specialized Pharmacy Services and Pharmacy Specialization”.

Dr Renly Lim, 01 Aug 2018
Palliative care uses an integrated, multidisciplinary approach to reduce suffering and to improve the quality of life of patients battling with life-threatening illnesses.
29 Jan 2017
The over-the-counter cough medicine CS1002 does not appear to induce a significant improvement in cough severity, although it may produce greater reductions in cough frequency and sleep disruption compared with simple linctus (SL), according to a study. Furthermore, the drug is associated with increased resolution of cough, resulting in early treatment discontinuation and improved health status.