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01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
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Heart rate implicated in death among acute stroke patients with atrial fibrillation

12 Dec 2019

The mean heart rate during acute stroke period factors in mortality but not stroke recurrence in patients with atrial fibrillation (AF) hospitalized for acute ischaemic stroke, a study has found. Heart rate variability has no effect on both outcomes.

Researchers used data from multicentre prospective stroke registry database and identified 3,622 ischaemic stroke patients (mean age, 74 years) who had AF and were hospitalized within 48 hours of stroke onset. They collected heart rate information in the acute stroke period, which was categorized as early (within 24 hours of hospitalization; n=2,046) and late (72 hours to 7 days from onset; n=1,576) stages.

In the entire cohort, 102 patients (5.0 percent) had a stroke recurrence and 440 (21.5 percent) died during the first year after stroke.

In the early acute stroke stage analysis, mean heart rate showed a statistically significant nonlinear J-shaped association with mortality (p<0.04 for quadratic and overall effect) but not with stroke recurrence (p>0.1 for quadratic and overall effect). Similar associations were observed in the late acute stroke stage analysis.

The nonlinear and overall effects of the coefficients of variation of heart rate were not significant for mortality and stroke recurrence.

According to the researchers, the findings can be partially explained by the knowledge that the increased risk of death in patients with elevated heart rates and in those with the lowest extreme of mean heart rate may be attributed to decreased heart function.

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Most Read Articles
01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
Roshini Claire Anthony, 29 May 2019

Gestational diabetes and abnormal glucose levels in pregnancy, as determined with an oral glucose challenge test (OGCT) at 24–28 weeks gestation, could signal a future risk of cardiovascular disease (CVD)*, according to a recent study.

07 Jul 2019
Plasma creatinine kinase activity, measure during early pregnancy, influences blood pressure during pregnancy and contributes to severe gestational hypertension diagnosed before 34 weeks of gestation, according to a recent study. There is no association between creatinine kinase and other hypertensive disorders during pregnancy.
Pank Jit Sin, 16 Oct 2019
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers.