Most Read Articles
6 days ago
Higher intake levels of coffee appear to be associated with reduced risk of developing chronic kidney disease, according to data from the Atherosclerosis Risk in Communities Study.
Jairia Dela Cruz, 4 days ago
Infants delivered via caesarean section may be at increased risk of developing acute lymphoblastic leukaemia, according to a US study. Altered microbiota colonization is a possible explanation for this risk, although clear biological mechanisms have yet to be established.
3 days ago
Treatment with danegaptide does not improve myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, according to the results of a phase II study.
3 days ago
Men with high levels of exposure to diesel exhaust are at greater risk of developing amyotrophic lateral sclerosis (AML), as shown in a recent study. This is not true for women.

H. pylori infection linked to increased hypertension prevalence

12 Mar 2018

There appears to be a positive association between Helicobacter pylori infection and prevalence of hypertension, according to a cross-sectional study of Chinese adults.

A total of 5,168 individuals (mean age 42.58 years; 39.4 percent female; 18.5 percent had hypertension) underwent a 13C-urea breath test and a routine health check-up. The prevalence rate of H. pylori infection was 32.6 percent.

Compared with those who were not infected, individuals with H. pylori infection were older; had higher body mass index, blood pressure, LDL and fasting plasma glucose; lower HDL; and were more likely to have higher prevalence of hypertension and diabetes mellitus (p<0.05 for all).

Logistic and linear regression analyses showed H. pylori infection to be associated with an increased prevalence of hypertension (odds ratio [OR], 1.23; 95 percent CI, 1.04–1.46). There were increases of 0.735 mm Hg in diastolic blood pressure and of 0.723 mm Hg in mean arterial pressure observed in individuals with H. pylori infection vs those without the infection.

In subgroup analyses, age, sex and body mass index did not significantly influence the observed association between H. pylori infection and the prevalence of hypertension (p>0.05 for all).

In light of the present data, researchers pointed out that strategies to prevent and eradicate H. pylori infection may have a significant effect on prevention and treatment of hypertension. More well-designed studies are needed to validate these findings.

The association between H. pylori infection and hypertension is said to be potentially mediated by high salt intake, which is a major risk factor for hypertension. High salt intake has been shown to stimulate the gastric mucosa and make it susceptible to infection with H. pylori.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
6 days ago
Higher intake levels of coffee appear to be associated with reduced risk of developing chronic kidney disease, according to data from the Atherosclerosis Risk in Communities Study.
Jairia Dela Cruz, 4 days ago
Infants delivered via caesarean section may be at increased risk of developing acute lymphoblastic leukaemia, according to a US study. Altered microbiota colonization is a possible explanation for this risk, although clear biological mechanisms have yet to be established.
3 days ago
Treatment with danegaptide does not improve myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, according to the results of a phase II study.
3 days ago
Men with high levels of exposure to diesel exhaust are at greater risk of developing amyotrophic lateral sclerosis (AML), as shown in a recent study. This is not true for women.