Most Read Articles
Jairia Dela Cruz, 22 Apr 2020
A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.
Roshini Claire Anthony, 27 May 2020

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Natalia Reoutova, Yesterday

A comprehensive review of neurological disorders reported during the current coronavirus disease 2019 (COVID-19) pandemic demonstrates that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the central nervous system (CNS), the peripheral nervous system (PNS) and muscles, leading the Environmental Neurology Specialty Group of the World Federation of Neurology to propose implementation of international neurological registries.

H. pylori-eradication therapy improves insulin sensitivity, hepatic steatosis in NAFLD

13 Jan 2020

Helicobacter pylori-eradication therapy (HPET) in patients with nonalcoholic fatty liver disease (NAFLD) leads to greater improvement in homeostasis model assessment-insulin resistance (HOMA-IR) but exerts comparable effects on hepatic steatosis and liver enzymes as compared with diet and exercise alone, a study has shown.

The trial included 80 NAFLD patients with H. pylori coinfection, 36 of which were assigned to receive standard management therapy (SMT; diet and exercise) and 44 to HPET (SMT plus amoxicillin, clarithromycin and pantoprazole).

A total of 28 patients in the SMT group and 36 in the HPET group were included in a modified intention-to-treat population. At week 24, controlled attenuation parameter (CAP) scores significantly decreased in the two groups (p=0.002 and p<0.001, respectively), without significant between-group difference (p=0.213).

H. pylori infection was successfully eradicated in 68 percent of patients in the HPET group. This group of patients showed greater improvement in HOMA-IR at week 24 compared to nonresponders or those treated with SMT (p=0.007).

There were also significant reductions observed in liver enzymes in both groups, although the changes between them were similar. Meanwhile, lipid parameters remained stable at week 24 . The HPET group exhibited a significant increase in the levels of reduced glutathione, but the change was not statistically different relative to the SMT group.

More studies involving a larger sample size, more effective HPET regimen and paired liver biopsy are needed for improved understanding, the researchers said.

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Most Read Articles
Jairia Dela Cruz, 22 Apr 2020
A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.
Roshini Claire Anthony, 27 May 2020

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Natalia Reoutova, Yesterday

A comprehensive review of neurological disorders reported during the current coronavirus disease 2019 (COVID-19) pandemic demonstrates that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the central nervous system (CNS), the peripheral nervous system (PNS) and muscles, leading the Environmental Neurology Specialty Group of the World Federation of Neurology to propose implementation of international neurological registries.