Most Read Articles
22 Jul 2020
A picosecond alexandrite laser (PSAL) appears to be superior to Q-switched alexandrite laser (QSAL) for the treatment of nevus of Ota, as shown by its better clinical results and fewer adverse events, according to a study.
Elvira Manzano, 28 Jul 2020
The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE+ study presented at ADA 2020.
3 days ago
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
Stephen Padilla, 28 Jul 2020
Higher levels of plasma vitamin C, total and individual carotenoid biomarkers, and their composite biomarker score appear to reduce the incidence of type 2 diabetes (T2D), according to the results of a prospective case-cohort study in eight European countries.

Gout bidirectionally related to diabetes mellitus after acute pancreatitis

15 Jun 2020

A bidirectional relationship exists between gout and diabetes mellitus in the postpancreatitis setting, suggests a recent study. Additionally, a history of gout is a predictor of postpancreatitis diabetes mellitus (PPDM) in women but not in men.

Individuals often have low-grade inflammation following acute pancreatitis and subsequently develop metabolic sequelae such as PPDM, according to the authors.

Risk analysis for gout included a total of 10,117 individuals, while that for PPDM included 9,471 participants. PPDM showed a significant correlation with a higher risk of gout in the overall cohort (adjusted hazard ratio [HR], 1.88, 95 percent confidence interval [CI], 1.15–3.06) and women (adjusted HR, 2.72, 95 percent CI, 1.31–5.65), but not in men (adjusted HR, 1.42, 95 percent CI, 0.73–2.78).

On the other hand, pre-existing gout also correlated with a higher risk of PPDM in the overall cohort (adjusted HR, 1.58, 95 percent CI, 1.04–2.41) and women (adjusted HR, 2.66, 95 percent CI, 1.29–5.49), but not in men (adjusted HR, 1.31, 95 percent CI, 0.78–2.20).

In this study, the authors used nationwide pharmaceutical dispensing data linked to hospital discharge data in New Zealand to identify gout and PPDM among individuals after first episode of acute pancreatitis between 1 January 2007 and 31 December 2015.

Multivariable Cox regression analyses were then performed, adjusting for age, sex, ethnicity, social deprivation index, alcohol consumption, tobacco smoking, comorbidities, medications (eg, glucocorticoids, statins, and oestrogens), and characteristics of acute pancreatitis.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
22 Jul 2020
A picosecond alexandrite laser (PSAL) appears to be superior to Q-switched alexandrite laser (QSAL) for the treatment of nevus of Ota, as shown by its better clinical results and fewer adverse events, according to a study.
Elvira Manzano, 28 Jul 2020
The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE+ study presented at ADA 2020.
3 days ago
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
Stephen Padilla, 28 Jul 2020
Higher levels of plasma vitamin C, total and individual carotenoid biomarkers, and their composite biomarker score appear to reduce the incidence of type 2 diabetes (T2D), according to the results of a prospective case-cohort study in eight European countries.