Most Read Articles
30 Sep 2019
Adolescents with primary enuresis nocturna (PEN) are more likely to have social anxiety (SA), a recent study has found.
Stephen Padilla, 18 Sep 2019
Use of complementary and alternative medicine (CAM) is common among patients with prostate cancer and has seen an increase among those who are newly diagnosed with the disease, a study has shown. Multivitamins and omega-3 fatty acids are the most commonly used CAMs from 1996 to 2016, while vitamin D use has increased dramatically from 2006 to 2010.
Audrey Abella, 30 Sep 2019
Cabozantinib was no better than the combination of mitoxantrone and prednisone for pain relief in heavily pretreated men with metastatic castration-resistant prostate cancer (mCRPC) and symptomatic bone metastases, according to the findings of the COMET-2* trial.

Good long-term QoL outcomes following postprostatectomy intensity-modulated radiation therapy

26 Oct 2019

Postprostatectomy intensity-modulated radiation therapy (PPRT) leads to favourable long-term quality of life (QoL) among prostate cancer patients without bearing substantial late toxicities, a recent study has found.

Researchers performed a prospective cohort study on 199 men (median age, 64 years) who underwent PRRT for prostate cancer. QoL was assessed using the Expanded Prostate Cancer Index Composite and adverse events were evaluated at every follow-up visit. Two-thirds (66 percent; n=132) of the participants received concomitant androgen deprivation therapy for a median of 4 months.

QoL scores across all domains remained stable over a median follow-up time of 33 months. There were no declines in scores that exceeded the minimum clinically important difference threshold.

Between 8 percent and 18 percent of the participants reported small declines in multiple QoL domains up to 84 months after PPRT. In the same time frame, 0 percent to 8 percent experienced a moderate decline.

The same was true for the use of sexual aids, which remained stable over time. Moreover, while participants reported a decline in functional erections immediately after PPRT, 59 percent had recovered by month 36 and showed a continuous upward trend over time.

“To our knowledge, this represents one of the few reports detailing QoL outcomes, including urinary pad and sexual aid usage, and identifying clinical and dosimetric predictors of decline in a large prospectively evaluated cohort receiving intensity-modulated PPRT,” said the researchers.

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Most Read Articles
30 Sep 2019
Adolescents with primary enuresis nocturna (PEN) are more likely to have social anxiety (SA), a recent study has found.
Stephen Padilla, 18 Sep 2019
Use of complementary and alternative medicine (CAM) is common among patients with prostate cancer and has seen an increase among those who are newly diagnosed with the disease, a study has shown. Multivitamins and omega-3 fatty acids are the most commonly used CAMs from 1996 to 2016, while vitamin D use has increased dramatically from 2006 to 2010.
Audrey Abella, 30 Sep 2019
Cabozantinib was no better than the combination of mitoxantrone and prednisone for pain relief in heavily pretreated men with metastatic castration-resistant prostate cancer (mCRPC) and symptomatic bone metastases, according to the findings of the COMET-2* trial.