Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.

Good long-term QoL outcomes following postprostatectomy intensity-modulated radiation therapy

26 Oct 2019

Postprostatectomy intensity-modulated radiation therapy (PPRT) leads to favourable long-term quality of life (QoL) among prostate cancer patients without bearing substantial late toxicities, a recent study has found.

Researchers performed a prospective cohort study on 199 men (median age, 64 years) who underwent PRRT for prostate cancer. QoL was assessed using the Expanded Prostate Cancer Index Composite and adverse events were evaluated at every follow-up visit. Two-thirds (66 percent; n=132) of the participants received concomitant androgen deprivation therapy for a median of 4 months.

QoL scores across all domains remained stable over a median follow-up time of 33 months. There were no declines in scores that exceeded the minimum clinically important difference threshold.

Between 8 percent and 18 percent of the participants reported small declines in multiple QoL domains up to 84 months after PPRT. In the same time frame, 0 percent to 8 percent experienced a moderate decline.

The same was true for the use of sexual aids, which remained stable over time. Moreover, while participants reported a decline in functional erections immediately after PPRT, 59 percent had recovered by month 36 and showed a continuous upward trend over time.

“To our knowledge, this represents one of the few reports detailing QoL outcomes, including urinary pad and sexual aid usage, and identifying clinical and dosimetric predictors of decline in a large prospectively evaluated cohort receiving intensity-modulated PPRT,” said the researchers.

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Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.