Glycaemic control, disease duration influence ED prevalence in diabetics

26 Jan 2019
Glycaemic control, disease duration influence ED prevalence in diabetics

Erectile dysfunction (ED) is common in type 2 diabetics, a recent China study has found. Worse glycaemic control and having a longer disease duration appear to contribute to the progression of ED.

A total of 550 men with type 2 diabetes mellitus (T2DM) participated in the study. The International Index of Erectile Function was used to diagnose and evaluate the severity of ED. All participants additionally underwent a physical examination, as well as an interview for demographic factors and medical history.

More than half (64.2 percent; n=318) of the participants had ED (mean age 51.3±12.6 years); the non-ED participants were, on average, 46.1±10.7 years old. Diabetes-related complications were more prevalent in the former group (59.1 percent vs 22.6 percent). The mean disease duration was 15.3±3.1 years, and the mean glycated haemoglobin concentration was 8.1±1.5 percent.

Glycaemic control appeared to have a significant effect on ED. The corresponding prevalence rates in participants with poor, fair and good control were 72.5 percent, 61.8 percent and 49.6 percent.

The same was true for disease duration. A larger proportion of those who have had T2DM for >10 years were positive for ED (88.7 percent) and severe ED (41.4 percent), relative to those who have had the disease for <5 years (40.5 percent and 6.3 percent, respectively).

ED prevalence also varied significantly with age. Among those >60, 41–60 and 21–40 years old, the prevalence rates of ED were 83.5 percent, 61.0 percent and 34.7 percent, respectively (p<0.0001). Similarly, severe ED was more common in the >60 vs 41–60 years age group (48.1 percent vs 18.2 percent). None of the participants <40 years of age had severe ED.

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