Most Read Articles
Jairia Dela Cruz, 13 Oct 2016
Children born to obese mothers are at increased risk of developing autism spectrum disorder (ASD) compared with children born to normal-weight mothers, according to data from a review and meta-analysis.
Yap Te-Lu, Anette Sundfor Jacobsen, 01 Oct 2013

Antenatal hydronephrosis (ANH) is a general term used to describe the dilatation of the fetal renal pelvis and/or its calyces. In pelviectasis, there is only dilatation of the renal pelvis; while in caliectasis, there is dilatation of the calyces. ANH is the most commonly diagnosed congenital urinary tract anomaly, which is detected by prenatal screening in 1–5% of all pregnancies

Yap Te-Lu, Anette Sundfor Jacobsen, 01 Dec 2012

Antenatal hydronephrosis (ANH) is a general term used to describe the dilatation of the fetal renal pelvis and/or its calyces. In pelviectasis, there is only dilatation of the renal pelvis; while in caliectasis, there is dilatation of the calyces. ANH is the most commonly diagnosed congenital urinary tract anomaly, which is detected by prenatal screening in 1–5% of all pregnancies.

Yap Te-Lu, Anette Sundfor Jacobsen, 01 Apr 2011

Antenatal hydronephrosis (ANH) is a general term used to describe the dilatation of the fetal renal pelvis and/or its calyces. In pelviectasis, there is only dilatation of the renal pelvis; while in caliectasis, there is dilatation of the calyces. ANH is the most commonly diagnosed congenital urinary tract anomaly, which is detected by prenatal screening in 1–5% of all pregnancies.

Glucomannan delivers limited benefits in children with constipation

13 Jul 2017

Glucomannan may increase the defecation frequency of children with constipation, but it may not have such favourable effects on stool consistency and the rate of successful treatment, according to the results of a systematic review and meta-analysis.

Researchers conducted a comprehensive electronic literature search to identify eligible randomized controlled trials (RCTs) that assessed the effectiveness of glucomannan. The results were reported as mean differences (MDs), standardized mean differences (SMDs) and risk ratios (RRs) with 95 percent CIs.

Defecation frequency per week was the primary outcome, and the secondary outcomes were stool consistency and the rate of successful treatment. The random effects model was used to conduct the meta-analysis.

A total of three RCTs were identified, which involved 122 participants. The use of glucomannan moderately increased the frequency of defecation (3 trials; MD, 1.40; 95 percent CI, 0.36 to 2.44; p=0.008) in children with constipation.

However, no significant differences were observed in the outcomes of stool consistency (3 trials; SMD, 0.48; ‒0.44 to 1.40; p=0.300) or the rate of successful treatment (2 trials; RR, 1.36; 0.48 to 3.81; p=0.110) among participants.

The results of this study should be cautiously interpreted because of the substantial biological, methodological and statistical heterogeneity among the RCTs, according to researchers.

“Additional large-scale, well-designed RCTs on this topic are required,” they said. “The effectiveness and side effects of long-term glucomannan use among children with constipation should be examined in the future in a more systematic manner.”

Constipation is a common complaint among children and significantly affects their quality of life, researchers noted.

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Most Read Articles
Jairia Dela Cruz, 13 Oct 2016
Children born to obese mothers are at increased risk of developing autism spectrum disorder (ASD) compared with children born to normal-weight mothers, according to data from a review and meta-analysis.
Yap Te-Lu, Anette Sundfor Jacobsen, 01 Oct 2013

Antenatal hydronephrosis (ANH) is a general term used to describe the dilatation of the fetal renal pelvis and/or its calyces. In pelviectasis, there is only dilatation of the renal pelvis; while in caliectasis, there is dilatation of the calyces. ANH is the most commonly diagnosed congenital urinary tract anomaly, which is detected by prenatal screening in 1–5% of all pregnancies

Yap Te-Lu, Anette Sundfor Jacobsen, 01 Dec 2012

Antenatal hydronephrosis (ANH) is a general term used to describe the dilatation of the fetal renal pelvis and/or its calyces. In pelviectasis, there is only dilatation of the renal pelvis; while in caliectasis, there is dilatation of the calyces. ANH is the most commonly diagnosed congenital urinary tract anomaly, which is detected by prenatal screening in 1–5% of all pregnancies.

Yap Te-Lu, Anette Sundfor Jacobsen, 01 Apr 2011

Antenatal hydronephrosis (ANH) is a general term used to describe the dilatation of the fetal renal pelvis and/or its calyces. In pelviectasis, there is only dilatation of the renal pelvis; while in caliectasis, there is dilatation of the calyces. ANH is the most commonly diagnosed congenital urinary tract anomaly, which is detected by prenatal screening in 1–5% of all pregnancies.