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Ginkgo biloba extract improves cognition and overall condition after ischaemic stroke

Christina Lau
23 Nov 2018
Dr Yanxin Zhao speaking at VasCog 2018

Use of a ginkgo biloba extract on top of standard preventive treatment is shown to improve cognitive function and overall condition after acute ischaemic stroke. 

In a multicentre pilot study, patients aged ≥50 years (n=201) who had an ischaemic stroke 7–14 days before baseline were randomized to receive standard treatment for prevention of stroke recurrence with or without EGb 761, a ginkgo biloba extract taken three times daily, for 24 weeks.

“Results showed significant improvements in cognitive function, mainly in memory, language, orientation and processing speed, in the EGb 761 vs standard treatment group, as assessed by Montreal Cognitive Assessment [MoCA] and Hopkins Verbal Learning Test [HVLT],” reported investigator Dr Yanxin Zhao of Fudan University, Shanghai, China, at VasCog 2018.

“Eighty percent of patients in the EGb 761 group had very much or much improved overall condition, compared with 20 percent of patients in the standard treatment group [p<0.05]. Neuropsychiatric symptoms and stroke-related symptoms were very mild at baseline, and improved slightly and to similar degrees in both groups,” he continued. “EGb 761 was safe and well tolerated in the study.”

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Most Read Articles
19 Sep 2016
Sertraline may prevent the onset of depressive disorders after traumatic brain injury (TBI), a randomized trial showed.
23 Jul 2019
Eating healthy foods, especially those following the Mediterranean dietary pattern, or avoiding proinflammatory diet appears to exert a protective effect on the risk of depression, according to a systematic review and meta-analysis.
09 Oct 2016
The use of hormonal contraception increases the risk of subsequent use of antidepressants and a first diagnosis of depression, results of a study show.
01 Dec 2016
Vortioxetine 5-20 mg/day lessens depression and anxiety severity in patients with major depressive disorder (MDD) and high levels of anxiety, as observed in a meta-analysis of 10 randomised, placebo-controlled, 6/8-week trials.