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Elvira Manzano, 6 days ago
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Yesterday
Monotherapy with tocilizumab (TCZ) shows good tolerability profile and results in remission in most patients with polymyalgia rheumatica (PMR) despite the absence of glucocorticoids, according to the 2-year results of a single-centre, open‐label pilot study.

Generalized, local dry skin common among middle-aged adults, seniors

24 Sep 2019

Generalized (GDS) and localized (LDS) dry skin is prevalent among middle-aged and elderly adults, a recent study has found.

The study included 5,547 participants (mean age, 70 years; 57 percent female), of whom 60 percent had dry skin. A further 20 percent of those with dry skin were severely affected and were ascertained to have GDS; the remaining had LDS.

Multivariate logistic regression analysis found that age was significantly correlated with the risk of both GDS (odds ratio [OR], 1.04, 95 percent CI, 1.03–1.05; p<0.01) and LDS (OR, 1.009, 1.003–1.016; p<0.01), as was the female sex (GDS: OR, 1.49, 1.16–1.93; LDS: OR, 1.29, 1.10–1.52; p<0.01 for both). In comparison, smoking increased the risk only of GDS (OR, 1.27, 1.02–1.57; p=0.03).

Body mass index, on the other hand, was inversely associated with GDS (OR, 0.96, 0.94–0.98) and LDS (OR, 0.98, 0.97–0.99; p<0.01 for both) risks. Daily cream use shared a similar relationship with LDS risk (OR, 0.77, 0.65–0.92; p<0.01), and the same was true between self-perceived health and the likelihood of GDS (OR, 0.993, 0.987–0.999; p=0.02).

In terms of comorbidities, eczema was associated with an increased risk of both GDS (OR, 7.04, 5.92–8.37) and LDS (OR, 2.44, 1.85–3.25; p<0.01 for both). Chemotherapy had the same effect (GDS: OR, 1.69, 0.97–2.95; p=0.07; LDS: OR, 1.56, 1.05–2.32; p=0.03).

Other pertinent risk factors included having itchy skin condition, seborrheic dermatitis and diabetes, as well as taking statins and diuretics.

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Most Read Articles
5 days ago
In patients with atrial fibrillation (AF) and stable coronary artery disease (CAD), rivaroxaban monotherapy is noninferior to combination treatment with an antiplatelet therapy in terms of cutting the risk of cardiovascular events and mortality, according to data from the AFIRE trial.
Elvira Manzano, 6 days ago
Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.
Jairia Dela Cruz, 3 days ago
Many patients with nonvalvular atrial fibrillation (NVAF) in Thailand use anticoagulants, but the uptake of nonvitamin-K oral anticoagulants remains suboptimal despite showing an upward trend, according to data from the COOL-AF registry presented at the European Society of Cardioloy (ESC) Asia Congress 2019 with APSC and AFC.
Yesterday
Monotherapy with tocilizumab (TCZ) shows good tolerability profile and results in remission in most patients with polymyalgia rheumatica (PMR) despite the absence of glucocorticoids, according to the 2-year results of a single-centre, open‐label pilot study.