Most Read Articles
Pearl Toh, 13 Jan 2018
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
Elvira Manzano, 4 days ago
Cancer patients at risk for recurrent venous thromboembolism (VTE) are less likely to experience recurrence with rivaroxaban compared with dalteparin, the Select-D trial has shown, ushering in a new standard of care (SoC) for cancer-related VTE.
Tristan Manalac, Yesterday
Hormone treatment confers beneficial mood effects in postmenopausal women, according to a recent study, which reports that a transdermal oestradiol plus intermittent micronized progesterone (TE+IMP) treatment regimen is more effective than placebo at reducing depressive symptoms in peri- and postmenopausal women.
3 days ago
Weight loss medications that have received the Food and Drug Administration (FDA) approval appear to confer only modest positive benefits for cardiometabolic risk profile, according to a study.

Gender, stressful events, early parenthood predict adolescent suicidality

14 Aug 2017
Singapore teenage suicide rates highest in 15 years

Gender, stressful life events and early parenthood are strong predictors of adolescent suicidality, a new study has shown.

The study included datasets from two longitudinal studies: The National Longitudinal Survey of Children and Youth (NLSCY) and the Avon Longitudinal Survey of Parents and Children (ALSPAC). The final sample size was 4,700. A Classification and Regression Tree (CART) model was built from the NLSCY cohort and validated in the ALSPAC cohort.

The primary outcome of the study was positive responses to questions about suicidal thoughts. Secondary outcomes included antisocial behaviour, substance abuse, poor physical health, poor mental health, poor academic performance and participation in risky health behaviours.

The overall weighted prevalence of suicidal thoughts was 12.0 percent in NLSCY cohort. CART showed that gender was the most powerful predictor of suicidal ideation. Stressful life events were the strongest predictor in females while early parental age was the strongest predictor in males.

Single parenthood, blended family composition, exposure to parental smoking, parental medical problems, lack of breast feeding and parental use of over-the-counter medications were also important predictors of suicidality.

The sensitivity and specificity of the model was 22.7 (95 percent CI, 19.4 to 26.1) and 89.2 (88.4 to 90.0) percent, respectively, while its positive and negative predictive values were 17.8 (15.1 to 20.50) and 91.8 (91.2 to 92.6) percent, respectively.

Validation against the ALSPAC cohort yielded a sensitivity and specificity of 19.9 (16.9 to 22.8) and 88.0 (87.0 to 89.0) percent, respectively. The resulting corresponding positive and negative predictive values were 22.5 (19.2 to 25.8) and 86.3 (85.2 to 87.3) percent.

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Most Read Articles
Pearl Toh, 13 Jan 2018
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
Elvira Manzano, 4 days ago
Cancer patients at risk for recurrent venous thromboembolism (VTE) are less likely to experience recurrence with rivaroxaban compared with dalteparin, the Select-D trial has shown, ushering in a new standard of care (SoC) for cancer-related VTE.
Tristan Manalac, Yesterday
Hormone treatment confers beneficial mood effects in postmenopausal women, according to a recent study, which reports that a transdermal oestradiol plus intermittent micronized progesterone (TE+IMP) treatment regimen is more effective than placebo at reducing depressive symptoms in peri- and postmenopausal women.
3 days ago
Weight loss medications that have received the Food and Drug Administration (FDA) approval appear to confer only modest positive benefits for cardiometabolic risk profile, according to a study.