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Tristan Manalac, 25 Jan 2020
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Gas tamponade an alternative treatment for myopic foveoschisis with foveal detachment

18 Aug 2019
The future of eyesight restoration may come from a most unlikely corneal donor – pigs.

Gas tamponade appears to be an effective alternative treatment for selected cases of myopic foveoschisis (FS) and foveal detachment (FD), suggests a recent study. In addition, the procedure may benefit patients without optical coherence tomography (OCT)-evident premacular membranes and who have a low height of FS.

A retrospective analysis was carried out to examine the long-term results of gas tamponade without vitrectomy in patients with myopic FS and FD. A total of 20 eyes from 20 patients with myopic FS and FD were included in the analysis. All patients were given an intravitreal injection of 0.2–0.3 mL C3F8 as initial treatment. They were followed for at least 18 months after the procedure.

The investigators assessed and recorded the refractive status, best-corrected visual acuity (BCVA), and anatomical abnormalities in macular area before and after the treatment.

At the 3-month follow-up visit, 14 eyes responded to initial gas tamponade and had FD resolved completely, while two eyes resolved FD partially. On the other hand, FD worsened in four eyes (nonresponders).

There were four eyes with increased detachment (two cases) or developed macular hole (two cases) that underwent vitrectomy. Two recurrent cases had repeated gas injection after initial success at the 3-month follow-up, and the FD was resolved anew. FA was resolved in 70 percent of eyes at the 3-month follow-up overall, and 65 percent were long-term responders to gas injection.

Treatment failure was predicted by the following factors: the presence of OCT-evident premacular membranes (p=0.03) and the height of FS >588 µm (p=0.009).

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