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Functional electrical stimulation effective for erectile dysfunction

09 Jul 2018

Functional electrical stimulation (FES) may be an effective treatment approach to erectile dysfunction, as it produces improvements in quality of life, according to a recent study.

Erectile dysfunction patients who received the FES intervention showed significant improvements from baseline in the erection hardness score (EHS; 1.73±0.13 to 2.82±0.3 points; p<0.0001; mean difference, 1.1 points; p<0.05).

Similar improvements were observed when the outcome was measured using the International Index of Erectile Function-5 (IIEF-5; 11±1.2 to 16±1.7 points; p<0.0001; mean difference, 5 points; p<0.05).

In contrast, no such improvements over time were seen in the patients who received the placebo intervention (EHS: 1.64±0.19 to 1.82±0.17 points; mean difference, 0.18 points; IIEF-5: 11.4±1.3 to 11.4±1.4 points; mean difference, 0 points).

In terms of quality of life, the FES intervention similarly produced significant improvements in all domains of the WHO Quality of Life instrument, except for the environment domain (physical health: 52.3±3 to 67.7±4.1; social relationships: 41.8±2.4 to 66.8±4; psychological: 47.3±2 to 67.3±2.9; p<0.0001 for all).

In comparison, placebo patients showed improvements only in the psychological (47.3±2.2 to 50.4±2) and social relationships (39.5±3.5 to 43.6±4.5; p<0.0001 for both) domains.

“Further studies should be carried [out] to corroborate our results, aiming to improve the methods of evaluation establishing the physiopathology pathways of the FES in the [nitric oxide] release, and finding selection criteria for patients suitable for this treatment,” said researchers.

For the present randomized controlled trial, 22 erectile dysfunction patients were randomized to receive either FES (50 Hz/500 µs; n=11; mean age 58.6±5.3 years) or placebo (n=11; mean age 58.4±5.8 years). FES was delivered during two weekly sessions each lasting 15 minutes. The trial duration was 4 weeks.

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Most Read Articles
4 days ago
Chocolate consumption is not associated with risk of coronary heart disease (CHD), stroke or both combined in postmenopausal women free of pre-existing major chronic disease, a study suggests.
Pearl Toh, 5 days ago
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.
4 days ago
Switching from thiazide diuretic to ipragliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, leads to improvements in metabolic parameters and body mass composition without affecting blood pressure in type 2 diabetes (T2D) patients, a recent study has found.
2 days ago
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