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Functional electrical stimulation effective for erectile dysfunction

09 Jul 2018

Functional electrical stimulation (FES) may be an effective treatment approach to erectile dysfunction, as it produces improvements in quality of life, according to a recent study.

Erectile dysfunction patients who received the FES intervention showed significant improvements from baseline in the erection hardness score (EHS; 1.73±0.13 to 2.82±0.3 points; p<0.0001; mean difference, 1.1 points; p<0.05).

Similar improvements were observed when the outcome was measured using the International Index of Erectile Function-5 (IIEF-5; 11±1.2 to 16±1.7 points; p<0.0001; mean difference, 5 points; p<0.05).

In contrast, no such improvements over time were seen in the patients who received the placebo intervention (EHS: 1.64±0.19 to 1.82±0.17 points; mean difference, 0.18 points; IIEF-5: 11.4±1.3 to 11.4±1.4 points; mean difference, 0 points).

In terms of quality of life, the FES intervention similarly produced significant improvements in all domains of the WHO Quality of Life instrument, except for the environment domain (physical health: 52.3±3 to 67.7±4.1; social relationships: 41.8±2.4 to 66.8±4; psychological: 47.3±2 to 67.3±2.9; p<0.0001 for all).

In comparison, placebo patients showed improvements only in the psychological (47.3±2.2 to 50.4±2) and social relationships (39.5±3.5 to 43.6±4.5; p<0.0001 for both) domains.

“Further studies should be carried [out] to corroborate our results, aiming to improve the methods of evaluation establishing the physiopathology pathways of the FES in the [nitric oxide] release, and finding selection criteria for patients suitable for this treatment,” said researchers.

For the present randomized controlled trial, 22 erectile dysfunction patients were randomized to receive either FES (50 Hz/500 µs; n=11; mean age 58.6±5.3 years) or placebo (n=11; mean age 58.4±5.8 years). FES was delivered during two weekly sessions each lasting 15 minutes. The trial duration was 4 weeks.

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Most Read Articles
Roshini Claire Anthony, 3 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 6 days ago
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
4 days ago
The simple Atrial fibrillation (AF) Better Care (ABC) pathway holistically updates the integrated care for AF patients and helps reduce the risk of adverse outcomes such as all-cause mortality, stroke/major bleeding/cardiovascular death and hospitalization, according to a study.
Yesterday
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.