Most Read Articles
21 Sep 2020
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Jairia Dela Cruz, 16 Sep 2020
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Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
Percutaneous coronary intervention (PCI), compared with coronary artery bypass grafting (CABG), in the revascularization of left main coronary artery (LMCA) disease may lead to death, myocardial infarction (MI), or stroke in patients with moderate or severe left ventricular (LV) dysfunction, reveals a study.

Fructosamine weakly correlated with HbA1c in obese diabetics

22 Aug 2020
73% of workers aged above 40 were also found to be overweight or obese.

A weakened correlation between fructosamine and glycated haemoglobin (HbA1c) levels may be indicative of obesity in type 2 diabetes (T2D) patients, reports a new study.

Researchers conducted a prospective, single-centre study including 112 T2D patients, in whom body fat mass and fat-free mass were measured using dual-energy x-ray absorptiometry, while visceral and subcutaneous fat areas were assessed using magnetic resonance imagine. Blood samples were withdrawn and subjected to the appropriate assays for the quantification of HbA1c and fructosamine.

The median body mass index (BMI) in the study population was 34.9 kg/m2, and patients were divided into two groups: those fell above (n=56; mean age, 55.8±11.0 years) or below (n=56; mean age, 59.1±11.9 years) the median BMI.

In the overall sample, fructosamine shared a strong and significant correlation with HbA1c (r, 0.532; p<0.0001). Analysis according to BMI, however, showed important differences. While the interaction remained strong in patients below the median BMI (r, 0.765; p<0.0001), the magnitude of the correlation was almost halved in those above the median (r, 0.358; p=0.007).

Moreover, the regression line was significantly steeper in patients below the median BMI than in those above, such as the slopes of the two lines were significantly different (p=0.002).

Aside from BMI and HbA1c, fructosamine levels were also significantly correlated with fasting blood glucose (r, 0.366; p<0.0001) and fat mass (r, –0.296; p=0.002). No such interactions were reported for fat-free mass, liver fat, subcutaneous fat, and visceral fat.

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Most Read Articles
21 Sep 2020
Chest pain appears to be the principal complaint of patients hospitalized with a first myocardial infarction (MI), particularly among those in the youngest age group, a study has found.
Jairia Dela Cruz, 16 Sep 2020
In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
Percutaneous coronary intervention (PCI), compared with coronary artery bypass grafting (CABG), in the revascularization of left main coronary artery (LMCA) disease may lead to death, myocardial infarction (MI), or stroke in patients with moderate or severe left ventricular (LV) dysfunction, reveals a study.