Most Read Articles
2 days ago
Older women with longer endogenous oestrogen exposure and hormone therapy use are at much higher odds of having favourable cognitive status in late life, a recent study suggests.
Tristan Manalac, 5 days ago
The likelihood of distal stent graft-induced new entry (dSINE) is compounded by an excessive distal oversizing ratio and chronic type B aortic dissection (TBAD), according to a new Singapore meta-analysis.
Elvira Manzano, Yesterday
Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.
2 days ago
Better sleep appears to weaken pain and fatigue in older, community-dwelling adults with hip or knee osteoarthritis (OA), reports a recent study.

Frailty Index, Comprehensive Geriatric Assessment predict mortality in seniors after colorectal surgery

22 Sep 2019

The 40-item Frailty Index (FI) and the Comprehensive Geriatric Assessment (CGA) are similarly predictive of 1-year mortality in elderly adults undergoing colorectal surgery, a recent study has found.

Researchers enrolled 99 elderly adults (mean age, 80.18±5.88 years; 62 percent male) who were scheduled to undergo elective gastrointestinal surgery. Geriatric assessment was performed 0–14 days before the procedure using the CGA and the 40-item FI. A Barthel Index telephone interview was administered after a year to assess long-term outcomes.

Colorectal cancer was the most prevalence diagnosis (88 percent), followed by gastric cancer (12 percent). More than half (63.6 percent) of the participants had deficits in more than three CGA domains and thus had a frail phenotype. The FI, in comparison, identified 50.5 percent as prefrail and 40.5 percent as frail.

Nineteen deaths were reported a year after surgery, resulting in a 1-year mortality rate of 19 percent. Receiver operating characteristic curve analysis revealed comparable capabilities of CGA (area under the curve [AUC], 0.72, 95 percent CI, 0.58–0.86) and FI (AUC, 0.70, 0.54–0.89; p=0.61) to predict mortality.

However, at a cutoff value of 0.19, FI showed a slight edge, with a sensitivity of 87.5 percent and specificity of 51.1 percent. CGA achieved its best predictive value at a threshold value of 3, where the sensitivity and specificity were 87.5 percent and 44.3 percent, respectively.

Multivariate logistic regression analysis identified decline in functional status (odds ratio [OR], 1.45, 95 percent CI, 1.03–2; p=0.033) and cancer stage (OR, 3.28, 0.91–11.8; p=0.069) as significant predictors of 1-year mortality.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
2 days ago
Older women with longer endogenous oestrogen exposure and hormone therapy use are at much higher odds of having favourable cognitive status in late life, a recent study suggests.
Tristan Manalac, 5 days ago
The likelihood of distal stent graft-induced new entry (dSINE) is compounded by an excessive distal oversizing ratio and chronic type B aortic dissection (TBAD), according to a new Singapore meta-analysis.
Elvira Manzano, Yesterday
Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.
2 days ago
Better sleep appears to weaken pain and fatigue in older, community-dwelling adults with hip or knee osteoarthritis (OA), reports a recent study.