Most Read Articles
Pearl Toh, 6 days ago
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
5 days ago
Transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) have comparable safety in low-risk surgical patients, reports a new meta-analysis.
3 days ago
Eating alone may help in weight management as findings of a recent study suggest that eating with friends lead to higher food intake.
Tristan Manalac, 2 days ago
A digital-first approach, iConnect, allows patients to have greater access to services and guidance and enables healthcare providers to deliver much better postdischarge care, according to Lim Cher Wee, chief operating officer of the Ministry of Health, Office for Healthcare Transformation of Singapore, in his presentation at the recently concluded AsiaPac19 Conference & Exhibition of the Healthcare Information and Management Systems Society (HIMSS 2019).

Frailty Index, Comprehensive Geriatric Assessment predict mortality in seniors after colorectal surgery

22 Sep 2019

The 40-item Frailty Index (FI) and the Comprehensive Geriatric Assessment (CGA) are similarly predictive of 1-year mortality in elderly adults undergoing colorectal surgery, a recent study has found.

Researchers enrolled 99 elderly adults (mean age, 80.18±5.88 years; 62 percent male) who were scheduled to undergo elective gastrointestinal surgery. Geriatric assessment was performed 0–14 days before the procedure using the CGA and the 40-item FI. A Barthel Index telephone interview was administered after a year to assess long-term outcomes.

Colorectal cancer was the most prevalence diagnosis (88 percent), followed by gastric cancer (12 percent). More than half (63.6 percent) of the participants had deficits in more than three CGA domains and thus had a frail phenotype. The FI, in comparison, identified 50.5 percent as prefrail and 40.5 percent as frail.

Nineteen deaths were reported a year after surgery, resulting in a 1-year mortality rate of 19 percent. Receiver operating characteristic curve analysis revealed comparable capabilities of CGA (area under the curve [AUC], 0.72, 95 percent CI, 0.58–0.86) and FI (AUC, 0.70, 0.54–0.89; p=0.61) to predict mortality.

However, at a cutoff value of 0.19, FI showed a slight edge, with a sensitivity of 87.5 percent and specificity of 51.1 percent. CGA achieved its best predictive value at a threshold value of 3, where the sensitivity and specificity were 87.5 percent and 44.3 percent, respectively.

Multivariate logistic regression analysis identified decline in functional status (odds ratio [OR], 1.45, 95 percent CI, 1.03–2; p=0.033) and cancer stage (OR, 3.28, 0.91–11.8; p=0.069) as significant predictors of 1-year mortality.

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Most Read Articles
Pearl Toh, 6 days ago
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
5 days ago
Transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) have comparable safety in low-risk surgical patients, reports a new meta-analysis.
3 days ago
Eating alone may help in weight management as findings of a recent study suggest that eating with friends lead to higher food intake.
Tristan Manalac, 2 days ago
A digital-first approach, iConnect, allows patients to have greater access to services and guidance and enables healthcare providers to deliver much better postdischarge care, according to Lim Cher Wee, chief operating officer of the Ministry of Health, Office for Healthcare Transformation of Singapore, in his presentation at the recently concluded AsiaPac19 Conference & Exhibition of the Healthcare Information and Management Systems Society (HIMSS 2019).