Most Read Articles
Dr. Joseph Delano Fule Robles, 5 days ago

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

5 days ago
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
High levels of marijuana exposure appear to not be longitudinally associated with prevalent albuminuria and substantial changes in estimated glomerular filtration rate by cystatin C (eGFRcys), a recent US epidemiological study has shown.
4 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.

Formula-fed infants gain weight more rapidly, out of proportion to linear growth

12 Aug 2017

Weight gain is quicker and out of proportion to linear growth among formula-fed infants compared with predominantly breastfed ones, a recent study has found.

To investigate the associations of infant feeding with trajectories of growth and body composition from birth to 7 months in healthy infants, researchers analysed 276 participants from a previous study of maternal vitamin D supplementation during lactation. Mothers used monthly feeding diaries to report the extent of breastfeeding.

Researchers measured infants’ anthropometrics and used dual-energy X-ray absorptiometry to evaluate body composition at 1, 4 and 7 months. Changes in infant size (z scores for weight, length and body mass index [BMI]) and body composition (fat and lean mas, body fat percentage) were compared between predominantly breastfed and formula-fed infants, adjusting in linear regression for sex, gestational age, race/ethnicity, maternal BMI, study site and socioeconomic status.

Of the participants, 214 (78 percent) were breastfed (median duration 7 months) and 62 were exclusively formula fed.

Formula-fed, compared with breastfed, infants had lower birth-weight z scores (‒0.22 vs 0.16; p<0.01) but gained more in weight and BMI through 7 months of age (weight z score difference, 0.37; 95 percent CI, 0.04 to 0.71; BMI z score difference, 0.35; 0 to 0.69). There was no difference seen in linear growth (z score difference, 0.05; ‒0.24 to 0.34).

Compared with breastfed infants, formula-fed ones gained more lean mass (difference, 303 g; 137 to 469 g) but not fat mass (difference, ‒42 g; ‒299 to 215 g).

“These differences were attributable to greater accretion of lean mass, rather than fat mass,” researchers said. “Any later obesity risk associated with infant feeding does not appear to be explained by differential adiposity gains in infancy.”

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Dr. Joseph Delano Fule Robles, 5 days ago

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

5 days ago
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
High levels of marijuana exposure appear to not be longitudinally associated with prevalent albuminuria and substantial changes in estimated glomerular filtration rate by cystatin C (eGFRcys), a recent US epidemiological study has shown.
4 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.