Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 4 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
Yesterday
The risk of stroke and subsequent mortality is significantly elevated in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), a recent study has shown.
Roshini Claire Anthony, 10 Jan 2018

Adding rifampicin to standard antibiotic therapy does not improve outcomes in individuals with Staphylococcus aureus (S. aureus) bacteraemia, the ARREST* trial shows. However, rifampicin may contribute towards a minor reduction in bacteraemia recurrence.

Fish, egg intake may prevent success of H. pylori eradication therapy

21 Aug 2017

High consumption of fish and egg appears to be negatively associated with successful Helicobacter pylori eradication therapy in H. pylori‒positive patients with gastritis and/or duodenal ulcers, a recent study has found.

Researchers examined the influence of food and nutrient intake on H. pylori eradication therapy in 4,014 participants who underwent endoscopy, were tested for serum antibodies to H. pylori (2,046 positive; 51.0 percent) and had their food intake assessed using a food-frequency questionnaire (FFQ).

Among those who tested positive, endoscopies showed gastritis and/or duodenal ulcers in a total of 389 patients (19.0 percent), who also tested positive for a 13C-urea breath test (UBT). The said patients were given 1-week H. pylori eradication treatment with lansoprazole, amoxicillin and clarithromycin and a second UBT 8 weeks after treatment.

Of these patients, 352 had complete demographic characteristics, serum lipid, insulin, glycated haemoglobin, C-reactive protein (CRP) and creatinine concentrations, as well as complete FFQs. Researchers used multivariate logistic regression analysis to determine factors correlated with successful H. pylori eradication therapy.

Overall, there was a 60.4-percent (235 of 389) success rate of H. pylori eradication therapy.

The factors associated with treatment failure were as follows: increased age (p=0.02), higher CRP concentration (p<0.01), higher dietary cholesterol (p<0.01) or egg intake (p<0.01), higher ω-3 (n–3) fatty acid (p=0.02) or fish intake (p=0.01), and higher vitamin D intake (p=0.02). In addition, a strong association existed between higher vitamin D intake and higher fish consumption.

This study was limited by the failure to investigate the antibiotic resistance of H. pylori, researchers said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 4 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
Yesterday
The risk of stroke and subsequent mortality is significantly elevated in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD), a recent study has shown.
Roshini Claire Anthony, 10 Jan 2018

Adding rifampicin to standard antibiotic therapy does not improve outcomes in individuals with Staphylococcus aureus (S. aureus) bacteraemia, the ARREST* trial shows. However, rifampicin may contribute towards a minor reduction in bacteraemia recurrence.