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Firefighters may be at higher risk of heart attack, stroke

19 Apr 2020

A recent study has shown an increased cardiovascular risk among firefighters than referent controls when comparing those within the same blood pressure (BP) category. This suggests that firefighters with elevated BP and hypertension may be at increased risk of adverse prognosis.

A total of 8,242 firefighters and 28,678 referent controls (aged >40 years) who underwent baseline health examinations in 2002 and 2003 were enrolled in this study. The authors examined records of hospitalization and mortality until 2015.

Subcohort analysis using a propensity score-matched (PSM) cohort, with respect to job classification, was performed to assess the causal effect of BP on major adverse cardiovascular events (MACEs).

Compared with normal BP, hypertension correlated with a significant increase in the risk of MACEs in both firefighters and the age–sex matched cohort. In participants with elevated BP, however, hypertension significantly increased MACE risk only among firefighters (hazard ratio [HR], 1.41, 95 percent confidence interval [CI], 1.06–1.88).

In the PSM cohort, the risk of death or hospitalization from MACEs (HR, 1.29, 95 percent CI, 1.14–1.47), myocardial infarction (HR, 1.24, 95 percent CI, 1.07–1.43) and ischaemic stroke (HR, 1.43, 95 percent CI, 1.12–1.82) was significantly higher among firefighters than controls.

In addition, MACE risk was higher in firefighters with elevated BP (HR, 1.58, 95 percent CI, 1.04–2.40), stage 1 (HR, 1.24, 95 percent CI, 1.00–1.52) and stage 2 (HR, 1.39, 95 percent CI, 1.13–1.71) hypertension than in PSM controls.

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Most Read Articles
Christina Lau, 02 Jan 2020

Tolvaptan improves dyspnoea, increases sodium levels and reduces body weight in patients with acute heart failure (HF) with or without hyponatraemia, but no significant effect is seen in mortality or rehospitalization, according to a recent meta-analysis.

Pearl Toh, 15 Apr 2020
Transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic stenosis who are at low surgical risk appears to be safe with low rates of death or disabling stroke at 30 days, according to a study presented at the ACC.20/WCC Virtual Meeting.