Most Read Articles
22 Jul 2020
A picosecond alexandrite laser (PSAL) appears to be superior to Q-switched alexandrite laser (QSAL) for the treatment of nevus of Ota, as shown by its better clinical results and fewer adverse events, according to a study.
Elvira Manzano, 6 days ago
The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE+ study presented at ADA 2020.
3 days ago
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
Stephen Padilla, 6 days ago
Higher levels of plasma vitamin C, total and individual carotenoid biomarkers, and their composite biomarker score appear to reduce the incidence of type 2 diabetes (T2D), according to the results of a prospective case-cohort study in eight European countries.

Fibromyalgia burden significant in patients with comorbid insomnia

01 Aug 2019

Fibromyalgia patients with comorbid insomnia more often receive prescription medications for fibromyalgia and use ambulatory care services relative to their counterparts without the sleep disorder, according to a study, suggesting that comorbidity with insomnia substantially increases its burden.

Researchers used data from the Longitudinal Health Insurance Database 2010 and analysed the medical records of 17,920 patients treated for fibromyalgia, among whom 5,466 had comorbid insomnia. Compared with those who had no comorbidity, those who did had higher ambulatory visits and costs per person-year for evaluating or treating fibromyalgia and other conditions. Interestingly, most of the ambulatory visits were for treating other conditions other than fibromyalgia.

Multivariable logistic regression analysis revealed comorbid insomnia to be associated with higher likelihood of future use of antidepressants (adjusted odds ratio (OR), 3.84; p<0.001), gabapentin (adjusted OR, 1.67; p<0.001), pregabalin (adjusted OR, 1.79; p=0.046), muscle relaxants (adjusted OR, 3.05; p<0.001), and opioids and tramadol (adjusted OR, 1.59; p<0.001).

Additionally, the presence of sleep disorder was associated with greater frequency of visits to ambulatory care services for both fibromyalgia (β, 1.79, 95 percent CI, 1.57–2.02; p<0.001) and other conditions (β, 108.51, 103.14–113.89; p<0.001).

Poor sleep may aggravate symptom distress and pain intensity in fibromyalgia patients, leading to an increase in the economic burden on the healthcare system, according to the researchers. This highlights the importance of effective management of sleep disturbances in the management of this population.

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Most Read Articles
22 Jul 2020
A picosecond alexandrite laser (PSAL) appears to be superior to Q-switched alexandrite laser (QSAL) for the treatment of nevus of Ota, as shown by its better clinical results and fewer adverse events, according to a study.
Elvira Manzano, 6 days ago
The efficacy and cardiovascular (CV) safety of the SGLT2* inhibitor empagliflozin vs DPP-4** inhibitors and GLP-1*** receptor agonists in real-world patients were demonstrated in two interim analyses of the EMPRISE+ study presented at ADA 2020.
3 days ago
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
Stephen Padilla, 6 days ago
Higher levels of plasma vitamin C, total and individual carotenoid biomarkers, and their composite biomarker score appear to reduce the incidence of type 2 diabetes (T2D), according to the results of a prospective case-cohort study in eight European countries.