Most Read Articles
29 Jul 2020
Adjunctive perampanel appears to be safe and effective for long-term treatment of patients with tonic‐clonic seizures, according to a posthoc analysis.
11 Aug 2020
During the Allergic Rhinitis (AR) Boot Camp held in conjunction with the Bayer Pharmacist Congress 2020, Professor Dr Baharudin Abdullah discussed the management of AR in the primary care setting and the importance of using patient profiles to guide the choice of antihistamines.
Elaine Soliven, 18 Sep 2020
Adding mepolizumab to standard of care treatment significantly reduces nasal polyp size and obstruction in adults with chronic rhinosinusitis with nasal polyps (CRSwNP), according to the SYNAPSE* study presented at ERS 2020.
Jairia Dela Cruz, 18 Feb 2020
Administering daily oral doses of adjunctive perampanel is safe and well tolerated in the treatment of young and older children with focal seizures or generalized tonic‐clonic seizures, in addition to yielding about 40–70 percent reduction in seizure frequency, according to data from the open-label 311 Core Study.

Ferric carboxymaltose corrects anaemia in peritoneal dialysis patients

14 Jan 2020

Treatment with intravenous (IV) ferric carboxymaltose (FCM) safely and effectively treats iron-deficiency anaemia in patients undergoing peritoneal dialysis (PD), as shown in a recent study.

The safety analysis included 91 PD patients (mean age, 57.7 years) who initiated FCM treatment, while the efficacy analysis involved 70 patients (mean age, 50.9 years). All patients had available follow-up data of up to 12 months.

There was no hypersensitivity reaction documented, nor were there instances of FCM discontinuation or dose adjustment due to a serious adverse event (SAE). The most common non-SAEs were headache (four events), mild hypotension (three events) and hypertension (two events), among others.

In terms of efficacy, a large portion of patients achieved ferritin levels of 200–800 ng/mL (68.6 percent), transferrin saturation (TSAT) >20 percent (78.4 percent), and TSAT >20 percent and ferritin >200 ng/mL (62.8 percent) after 12 months of FCM initiation (p<0.01). Haemoglobin (Hb) levels remained at >11 g/dL with a lower dose of darbepoetin throughout the follow-up.

A subgroup analysis of patients naïve to IV iron and with absolute vs relative iron deficiency (n=51) revealed that 76.5 percent had ferritin levels >200 ng/mL, 80.4 percent had TSAT >20 percent, and Hb levels increased (1.2 g/dL) following 4 months of FCM treatment (p<0.01).

Although prospective studies are warranted, the present data indicate that “a high-dose and low-frequency strategy with FCM concurrent with routine hospital visits could be easily adapted to home PD,” researchers said.

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Most Read Articles
29 Jul 2020
Adjunctive perampanel appears to be safe and effective for long-term treatment of patients with tonic‐clonic seizures, according to a posthoc analysis.
11 Aug 2020
During the Allergic Rhinitis (AR) Boot Camp held in conjunction with the Bayer Pharmacist Congress 2020, Professor Dr Baharudin Abdullah discussed the management of AR in the primary care setting and the importance of using patient profiles to guide the choice of antihistamines.
Elaine Soliven, 18 Sep 2020
Adding mepolizumab to standard of care treatment significantly reduces nasal polyp size and obstruction in adults with chronic rhinosinusitis with nasal polyps (CRSwNP), according to the SYNAPSE* study presented at ERS 2020.
Jairia Dela Cruz, 18 Feb 2020
Administering daily oral doses of adjunctive perampanel is safe and well tolerated in the treatment of young and older children with focal seizures or generalized tonic‐clonic seizures, in addition to yielding about 40–70 percent reduction in seizure frequency, according to data from the open-label 311 Core Study.