Most Read Articles
Dr Margaret Shi, 18 May 2020

A blood test is shown to be feasible and safe for early detection of multiple cancers in women with no current or known history of cancer, enabling early treatment with curative intent in a subset of individuals.

Christina Lau, 20 Apr 2020

Hippocampal avoidance during whole-brain radiotherapy (HA-WBRT), together with memantine, better preserves cognitive function vs WBRT plus memantine in patients with brain metastases, without compromising survival, a multi-institutional phase III trial has shown.

Natalia Reoutova, 20 May 2020

Cancer patients infected with coronavirus disease 2019 (COVID-19) appear to be at higher risk of severe outcomes, including death, but cancer type and treatment serve as better predictors, according to recent research presented at the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting I.

At the time of writing, COVID-19 has spread to more than 200 countries and territories, affecting an estimated 4.5 million people and killing over 300,000. Cancer, on the other hand, is newly diagnosed in 18 million people and takes the lives of 10 million every year.

“We have invited physician scientists who are at the epicentre of the COVID-19 pandemic, taking care of patients with cancer. They gathered prospective information to understand the effects of COVID-19 on patients with cancer, are testing new treatments, and are making this knowledge available to the global research community, so we can all benefit from their experience,” said Professor Antoni Ribas from UCLA Medical Center, Los Angeles, California, US, chairperson of the COVID-19 and cancer plenary session of the meeting.

Natalia Reoutova, 28 May 2020

Fasting-mimicking diet (FMD) cycles in combination with endocrine therapy (ET) cause metabolic changes in hormone receptor (HR)-positive breast cancer patients analogous to those observed in animal models, where they are associated with anticancer activity.

Fear of falling has multifactorial roots in elderly adults with cancer

29 Apr 2020

Several mental and physical factors, including cognitive status and prior falls, contribute to the fear of falling (FOF) among elderly adults with cancer, a recent study has found.

Accessing the International Mobility in Ageing Study, researchers identified 175 elderly adults (mean age, 69.3 years; 50.2 percent female) who self-identified as cancer patients. The primary outcome was FOF, as measured by the Falls Efficacy Scale-International (FES-I). A parallel group of 177 healthy, age-matched participants was also enrolled.

In cancer patients, FOF varied significantly according to clinical variables. In particular, FES-I scores were higher among patients with a high burden of depressive symptoms, poor physical performance status and a history of falls in the prior year.

Multiple linear regression analysis confirmed that depressive symptoms, as measured by the Centre of Epidemiological Studies-Depression tool, was a risk factor for FOF with borderline significance (estimate, 0.16; p=0.09). In comparison, the number of falls in the last 12 months was able to significantly predict FOF (estimate, 0.93; p=0.01).

On the other hand, global cognition, as measured by the Leganes Cognitive Test (estimate, –1.35; p=0.00), and physical performance (estimate, –2.23; p<0.0001) were both significantly but negatively correlated with FOF.

“This study found that FOF is multifactorial in people with cancer,” the researchers said. “Recognizing and designing an intervention that targets these factors would help in reducing the impact of FOF in people with cancer.”

“This study lays the groundwork for future studies of cancer and FOF that include a broader range of risk factors,” they added.

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Most Read Articles
Dr Margaret Shi, 18 May 2020

A blood test is shown to be feasible and safe for early detection of multiple cancers in women with no current or known history of cancer, enabling early treatment with curative intent in a subset of individuals.

Christina Lau, 20 Apr 2020

Hippocampal avoidance during whole-brain radiotherapy (HA-WBRT), together with memantine, better preserves cognitive function vs WBRT plus memantine in patients with brain metastases, without compromising survival, a multi-institutional phase III trial has shown.

Natalia Reoutova, 20 May 2020

Cancer patients infected with coronavirus disease 2019 (COVID-19) appear to be at higher risk of severe outcomes, including death, but cancer type and treatment serve as better predictors, according to recent research presented at the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting I.

At the time of writing, COVID-19 has spread to more than 200 countries and territories, affecting an estimated 4.5 million people and killing over 300,000. Cancer, on the other hand, is newly diagnosed in 18 million people and takes the lives of 10 million every year.

“We have invited physician scientists who are at the epicentre of the COVID-19 pandemic, taking care of patients with cancer. They gathered prospective information to understand the effects of COVID-19 on patients with cancer, are testing new treatments, and are making this knowledge available to the global research community, so we can all benefit from their experience,” said Professor Antoni Ribas from UCLA Medical Center, Los Angeles, California, US, chairperson of the COVID-19 and cancer plenary session of the meeting.

Natalia Reoutova, 28 May 2020

Fasting-mimicking diet (FMD) cycles in combination with endocrine therapy (ET) cause metabolic changes in hormone receptor (HR)-positive breast cancer patients analogous to those observed in animal models, where they are associated with anticancer activity.