Most Read Articles
21 Mar 2018
During the Kuala Lumpur International Neonatology Conference held in conjunction with the World Prematurity Day 2017, Dato Dr Musa Mohd Nordin spoke on the importance of immunizing children with the diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine. He highlighted the role of Hexaxim® as a fully liquid, ready-to-use, 6-in-1 (including hepatitis B) vaccine for the primary and booster vaccinations of infants and toddlers. Meanwhile, Dr Yong Junina Fadzil discussed the benefits of quadrivalent influenza vaccines (QIVs) in providing children with broader protection against influenza B viruses.
Kavitha G. Shekar, 19 Aug 2015
Haematologic disorder, increasing age, malar rash, and autoantibodies are early predictors of arthritis in paediatric patients with systemic lupus erythematosus (SLE), a longitudinal cohort study has shown.
01 Dec 2017
Bifidobacteria supplementation to infant diet helps curb the occurrence of specific bacteria and metabolites during early life, a recent study has shown, adding that no long-term effects have been detected.

Exposure to cigarette smoke, air pollution ups risk of juvenile idiopathic arthritis

08 Feb 2018

Exposure to ozone (O3) in the second year of life and cigarette smoke (intrauterine and after birth) and maternal occupational exposure may increase the risk of juvenile idiopathic arthritis (JIA), suggests a recent study.

Intrauterine cigarette smoke exposure (odds ratio [OR], 3.43; 95 percent CI, 1.45‒8.12; p=0.005) and maternal occupational exposure (OR, 13.69; 4.4‒42.3; p<0.001) during pregnancy significantly independently predicted JIA. On the other hand, maternal employment (OR, 0.06; 0.02‒0.2; p<0.001) and ideal maternal weight gain (OR, 0.36; 0.2‒0.8; p=0.017) showed negative associations.

Furthermore, secondhand smoke exposure from birth to JIA diagnosis (OR, 3.6; 1.8‒7.3; p<0.001) and O3 exposure during the second year of life (OR, 2.76; 1.20‒6.37; p=0.017) were significant independent risk factors for the development of JIA.

A total of 66 patients with JIA and 124 age- and sex-matched healthy controls, living in Sao Paulo, Brazil, metropolitan area until JIA diagnosis, and whose mothers resided in this region during pregnancy were included in this exploratory case-control study.

The authors used a structured and reliable questionnaire (κ index for test-retest was 0.80) to analyse demographic data, gestational and perinatal-related factors, and exposure to inhalable environmental elements during pregnancy and after birth (occupational exposure to inhalable particles or volatile vapour, cigarette smoke exposure, and presence of industrial activities or gas stations near the home, work, daycare or school).

Tropospheric pollutants included particulate matter, sulphur dioxide, nitrogen dioxide, O3 and carbon monoxide.

The finding of an association between JIA and exposure to cigarette smoke and air pollution warrants further study, according to the authors.

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Most Read Articles
21 Mar 2018
During the Kuala Lumpur International Neonatology Conference held in conjunction with the World Prematurity Day 2017, Dato Dr Musa Mohd Nordin spoke on the importance of immunizing children with the diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine. He highlighted the role of Hexaxim® as a fully liquid, ready-to-use, 6-in-1 (including hepatitis B) vaccine for the primary and booster vaccinations of infants and toddlers. Meanwhile, Dr Yong Junina Fadzil discussed the benefits of quadrivalent influenza vaccines (QIVs) in providing children with broader protection against influenza B viruses.
Kavitha G. Shekar, 19 Aug 2015
Haematologic disorder, increasing age, malar rash, and autoantibodies are early predictors of arthritis in paediatric patients with systemic lupus erythematosus (SLE), a longitudinal cohort study has shown.
01 Dec 2017
Bifidobacteria supplementation to infant diet helps curb the occurrence of specific bacteria and metabolites during early life, a recent study has shown, adding that no long-term effects have been detected.