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08 Aug 2016
A new study shows that postural change affects the difference between intraocular pressure (IOP) and intracranial pressure (ICP) at the level of lamina cribrosa.

Exercise may cut risk of falling in seniors with neuropsychiatric symptoms

06 Nov 2018
A new study showed that exercise during middle age is linked with better cognition later in life.

In community-dwelling elderly adults with Alzheimer’s disease (AD) and neuropsychiatric symptoms (NPS), physical exercise appears to reduce the risk of falling, a recent study has shown.

Researchers enrolled 179 elderly adults with AD who completed the Neuropsychiatric Inventory (NPI). Participants were randomly assigned to receive an exercise intervention (n=120; mean age 77.6±5.3 years; 63.3 percent male) or the usual community care control (n=59; mean age 78.1±5.3 years; 57.6 percent male).

Thirty-six percent (n=43) of those randomized to the intervention group fell in the year prior to the trial. This was not significantly different from that in the control group (46 percent; n=27; p=0.20). In contrast, fall rate was significantly elevated in the control vs intervention group during the same year of the trial (2.87 vs 1.48 falls per person-year; incidence rate ratio, 0.48; 95 percent CI, 0.39–0.60; p<0.001).

Moreover, researchers observed a clear and linear relationship between fall incidence and NPI score in the control group (p=0.009 for interaction). Such an interaction was absent in the intervention group.

These findings were in spite of comparable baseline characteristics. Mini-Mental State Examination Scores were statistically similar between the intervention and control groups (18.8±6.3 vs 17.8±6.0; p=0.17), as were scores in the Short Physical Performance Battery (9.7±2.2 vs 9.9±2.0; p=0.70).

The findings of the present study thus indicate that exercise appears to have a protective effect against the risk of falls attributable to NPS, said researchers. However, future studies should investigate this relationship more carefully.

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Most Read Articles
08 Aug 2016
A new study shows that postural change affects the difference between intraocular pressure (IOP) and intracranial pressure (ICP) at the level of lamina cribrosa.