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01 Dec 2020
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Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 3 days ago
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Exercise essential for quality of life in middle-age, elderly individuals

06 Sep 2020

Performing moderate-to-vigorous physical activity (MVPA) plays an important role in the quality of life (QoL) of middle-age and elderly individuals, a study suggests.

Researchers looked at 1,934 participants aged 51–94 years (mean, 70.9 years; 51.5 percent female) from the 2011–2016 Rotterdam Study. These individuals slept a mean of 6.43 hours nightly and spent a mean of 13.54 hours being sedentary.

Daily, the participants performed light-intensity physical activity (LIPA) for 148.11±31.54 minutes and MVPA for 82.72±28.74 minutes. Their mean QoL EQ-5D-3L index score at baseline was 0.87.

Reallocation of 30 minutes from sedentary behaviour, LIPA, or sleep to MVPA was associated with a higher QoL. For instance, spending 30 minutes doing MVPA instead of being sedentary conferred a 3-percent increase in QoL score.

Conversely, reallocation from MVPA to sedentary behaviour, LIPA, or sleep was associated with lower QoL. For example, cutting back MVPA time by 30 minutes and spending it in sedentary behaviour contributed to a 4-percent drop in QoL score.

The present data may have implications for public health, indicating that the associated harm of less MVPA outweighs the benefit of more MVPA. Interventions should focus on preventing a decline rather than increasing PA for middle-age and elderly individuals with already high levels of PA. This could be effective during the colder months of the year, in certain life stages, or after specific life events, when time spent in MVPA typically tends to decline.

Additional studies are needed to explore causality.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 3 days ago
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.
3 days ago
Use of thyroid hormone therapy does not seem to protect older adults with subclinical hypothyroidism against mortality, but it appears to confer survival benefits to those aged <65 years, results of a study have shown.