Most Read Articles
Roshini Claire Anthony, 2 days ago

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

4 days ago
Eating behaviours have been shown to moderate the relationship between cumulated risk factors in the first 1,000 days and adiposity outcomes at 6 years of age, which underscores modifiable behavioural targets for interventions, reports a study.
Stephen Padilla, 3 days ago
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
Tristan Manalac, 6 days ago
Minimally invasive pancreatectomy (MIP) offers a feasible alternative to open pancreatectomy (OP) for the treatment of pancreatic neuroendocrine neoplasms (PNEN), according to a recent Singapore study has found.

Excessive daytime sleepiness predicts Aβ deposition

13 Sep 2018
The latest HLI survey had Hong Kong ranking last among 15 economies where "health satisfaction" was concerned.

Excessive daytime sleepiness (EDS) appears to increase the long-term risk of amyloid β (Aβ) deposition, a recent study has shown.

Using self-reports, researchers determined EDS and napping patterns in 124 community-dwelling adults (mean age 60.1±9.8 years; 50 percent female). Almost a third (29 percent) of the participants were nappers while 24 percent had EDS. There was no significant correlation between EDS and napping (p=0.24).

Pittsburgh compound B positron emission tomography scans were performed after a mean follow-up duration of 15.7±3.4 years to assess Aβ deposition. At the time of imaging, 4.8 percent (n=6) had been diagnosed with mild cognitive impairment and 34.7 percent (n=43) were positive for Aβ deposits.

Participants with self-reported EDS were significantly more likely to test positive for Aβ deposits at follow-up (56.7 percent vs 28.0 percent; p=0.004).

After adjustments for covariates, multivariable logistic regression analysis showed that the risk of Aβ deposition was 2.75 times higher in those with EDS than in those without (odds ratio [OR], 2.75; 95 percent CI, 1.09–6.95; p=0.033).

A similar trend was observed for nappers. In unadjusted analysis, those with self-reported napping were twice as likely to test positive for Aβ deposits on follow-up than non-nappers, though significance was not reached (OR, 2.01; 0.91–4.50; p=0.091). This relationship was attenuated upon controlling for covariates (OR, 1.86; 0.73–4.75; p=0.194).

The findings indicate that EDS may be a low-cost, simple and noninvasive method with which patients can be risk-stratified according to likelihood of Aβ deposition, said researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 2 days ago

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

4 days ago
Eating behaviours have been shown to moderate the relationship between cumulated risk factors in the first 1,000 days and adiposity outcomes at 6 years of age, which underscores modifiable behavioural targets for interventions, reports a study.
Stephen Padilla, 3 days ago
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
Tristan Manalac, 6 days ago
Minimally invasive pancreatectomy (MIP) offers a feasible alternative to open pancreatectomy (OP) for the treatment of pancreatic neuroendocrine neoplasms (PNEN), according to a recent Singapore study has found.