Most Read Articles
06 Dec 2018
A strong belief in the necessity of medication is associated with better adherence to oral disease-modifying antirheumatic drugs (DMARDs) or prednisone, while higher self-efficacy correlates with poor adherence, in a diverse cohort of patients with rheumatoid arthritis (RA), suggests a study.
Pearl Toh, 22 hours ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
6 days ago
Low-dose administrations of haloperidol after thoracic surgery does not appear to prevent postoperative delirium, according to a new study.
4 days ago
Percutaneous coronary intervention (PCI) displays comparable rates of mortality and serious composite outcomes but a higher rate of target-vessel revascularization at 10 years relative to coronary artery bypass grafting (CABG) in patients with significant left main coronary artery (LMCA) disease, reports a study. On the other hand, CABG delivers lower mortality and serious composite outcome rates compared with PCI with drug-eluting stents after 5 years.

Ex-vivo renal surgery feasible for complex renal conditions

11 Jan 2018
Surgeons were alleged to have permanently disabled a kidney cancer patient by removing his healthy kidney instead of the affected organ.

It appears that ex-vivo renal surgery may be performed for complex renal pathologies, but it is necessary to carefully select patients to achieve positive outcomes, a recent study suggests.

The investigators examined three patients who underwent ex-vivo renal surgery and autotransplantation for benign and malignant renal conditions. The procedures were performed in the urology and transplant departments between July 2015 and January 2016.

Patient 1 was a 63-year-old man presenting with spontaneous bleed from a renal mass in a solitary functional right kidney. Patient 2 was a 50-year-old man with bilateral renal tumours involving renal veins. Finally, patient 3 was a 50-year-old man with two previous failed right-sided pyeloplasties.

Of the three patients included in the study, none had intraoperative complications. Patient 1 had laparoscopic nephrectomy, ex-vivo partial nephrectomy followed by autotransplantation. No disease recurrence happened after a 6-month follow-up, and renal functions were stable.

Bilateral open radical nephrectomies were carried out in patient 2. Autotransplantation was performed on the right kidney following ex-vivo partial nephrectomy. On the left, a further procedure was cancelled after radical nephrectomy because of extensive disease involvement. The patient became anuric with poor Doppler signals after the procedure.

Following exploration, surgeons suggested complete renal vein obstruction with infarction of the autotransplanted right kidney requiring nephrectomy. There was disease recurrence found at the native renal bed at 6 months’ follow-up.

Finally, patient 3 underwent laparoscopic nephrectomy, ex-vivo pyeloplasty and autotransplantation. The patient was asymptomatic with stable renal functions at 12 months’ follow-up.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
06 Dec 2018
A strong belief in the necessity of medication is associated with better adherence to oral disease-modifying antirheumatic drugs (DMARDs) or prednisone, while higher self-efficacy correlates with poor adherence, in a diverse cohort of patients with rheumatoid arthritis (RA), suggests a study.
Pearl Toh, 22 hours ago
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
6 days ago
Low-dose administrations of haloperidol after thoracic surgery does not appear to prevent postoperative delirium, according to a new study.
4 days ago
Percutaneous coronary intervention (PCI) displays comparable rates of mortality and serious composite outcomes but a higher rate of target-vessel revascularization at 10 years relative to coronary artery bypass grafting (CABG) in patients with significant left main coronary artery (LMCA) disease, reports a study. On the other hand, CABG delivers lower mortality and serious composite outcome rates compared with PCI with drug-eluting stents after 5 years.