Most Read Articles
Stephen Padilla, 3 days ago
Treatment with oral thrombopoietin receptor agonist eltrombopag leads to similar platelet counts in patients with chronic immune thrombocytopaenia (cITP) and persistent (per)ITP, according to the results of phase III (EXTEND) and IV studies presented at the 23rd Congress of the European Hematology Association (EHA 2018) held in Stockholm, Sweden.
4 days ago
Socioeconomic status, along with other social determinants, appears to influence the long-term outcomes in Asian acute heart failure patients, according to a recent Japan study.
Pearl Toh, 6 days ago
Lonely people were twice as likely to die from any cause than people who did not feel lonely, according to a study based on a national survey presented at the recent EuroHeartCare 2018 in Dublin, Ireland. Also, loneliness is associated with poorer patient-reported outcomes in terms of mental and physical health in patients with heart disease.
Jairia Dela Cruz, 3 days ago
A treatment regimen combining daratumumab plus bortezomib, melphalan and prednisone markedly extends progression-free survival in patients with multiple myeloma, inducing deep responses and demonstrating acceptable tolerability regardless of baseline renal function, according to the results of the phase III ALCYONE study.

Ex-vivo renal surgery feasible for complex renal conditions

11 Jan 2018
Surgeons were alleged to have permanently disabled a kidney cancer patient by removing his healthy kidney instead of the affected organ.

It appears that ex-vivo renal surgery may be performed for complex renal pathologies, but it is necessary to carefully select patients to achieve positive outcomes, a recent study suggests.

The investigators examined three patients who underwent ex-vivo renal surgery and autotransplantation for benign and malignant renal conditions. The procedures were performed in the urology and transplant departments between July 2015 and January 2016.

Patient 1 was a 63-year-old man presenting with spontaneous bleed from a renal mass in a solitary functional right kidney. Patient 2 was a 50-year-old man with bilateral renal tumours involving renal veins. Finally, patient 3 was a 50-year-old man with two previous failed right-sided pyeloplasties.

Of the three patients included in the study, none had intraoperative complications. Patient 1 had laparoscopic nephrectomy, ex-vivo partial nephrectomy followed by autotransplantation. No disease recurrence happened after a 6-month follow-up, and renal functions were stable.

Bilateral open radical nephrectomies were carried out in patient 2. Autotransplantation was performed on the right kidney following ex-vivo partial nephrectomy. On the left, a further procedure was cancelled after radical nephrectomy because of extensive disease involvement. The patient became anuric with poor Doppler signals after the procedure.

Following exploration, surgeons suggested complete renal vein obstruction with infarction of the autotransplanted right kidney requiring nephrectomy. There was disease recurrence found at the native renal bed at 6 months’ follow-up.

Finally, patient 3 underwent laparoscopic nephrectomy, ex-vivo pyeloplasty and autotransplantation. The patient was asymptomatic with stable renal functions at 12 months’ follow-up.

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Most Read Articles
Stephen Padilla, 3 days ago
Treatment with oral thrombopoietin receptor agonist eltrombopag leads to similar platelet counts in patients with chronic immune thrombocytopaenia (cITP) and persistent (per)ITP, according to the results of phase III (EXTEND) and IV studies presented at the 23rd Congress of the European Hematology Association (EHA 2018) held in Stockholm, Sweden.
4 days ago
Socioeconomic status, along with other social determinants, appears to influence the long-term outcomes in Asian acute heart failure patients, according to a recent Japan study.
Pearl Toh, 6 days ago
Lonely people were twice as likely to die from any cause than people who did not feel lonely, according to a study based on a national survey presented at the recent EuroHeartCare 2018 in Dublin, Ireland. Also, loneliness is associated with poorer patient-reported outcomes in terms of mental and physical health in patients with heart disease.
Jairia Dela Cruz, 3 days ago
A treatment regimen combining daratumumab plus bortezomib, melphalan and prednisone markedly extends progression-free survival in patients with multiple myeloma, inducing deep responses and demonstrating acceptable tolerability regardless of baseline renal function, according to the results of the phase III ALCYONE study.