Most Read Articles
01 Dec 2019
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Roshini Claire Anthony, 6 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

01 Dec 2019
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.

Even low-impact exercise improves sleep in women

03 Nov 2019
Walking or taking the stairs are both effective to burn excess calories

Low-impact physical activity may have positive benefits on sleep quality, especially in women, a recent study has shown.

The study included 59 participants (mean age, 49.64±8.31 years; 73 percent female) who were healthy enough to walk briskly and worked full time. Participants were randomly assigned to either take 2,000 more steps per day relative to their baseline (intervention group) or to no weekly step goals (control group). Physical activity was measured using the Fitbit Zip, while sleep was assessed using the Pittsburgh Sleep Quality Index (PSQI).

Mean global PSQI scores did not change significantly from pre- to post-test (5.37±3.31 vs 5.04±3.28; p=0.37), and the interaction of time and condition also failed to reach statistical significance (p=0.46). The same was true for sleep duration (time: p=0.44; time-by-condition: p=0.29) and sleep efficiency (time: p=0.34; time-by-condition: p=0.70).

However, researchers found a moderating effect of sex on the relationship between daily number of steps and sleep quality. In particular, women who took more steps and spent more time engaging in physical activity were more likely to sleep better. This effect was not evident in men.

Despite no clear between-treatment differences, within-person analyses found that, after controlling for age, sex and intervention condition, participants reported significantly better sleep quality on days in which they accumulated more daily steps than usual (p=0.05). The number of steps had the same effect on sleep duration (p=0.05).

Moreover, on days where participants were able to engage in more active minutes than average, they also reported significantly better sleep quality (p=0.05) and longer sleep duration (p=0.04).

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Most Read Articles
01 Dec 2019
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Roshini Claire Anthony, 6 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

01 Dec 2019
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.