Most Read Articles
29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.
Pearl Toh, 12 Sep 2020
Early initiation of rhythm-control therapy led to a significantly reduced risk of major adverse cardiovascular (CV) outcomes compared with usual care (typically rate control) in patients with newly diagnosed atrial fibrillation (AF) at risk of stroke, reveals the EAST-AFNET 4* trial presented at ESC 2020.
Audrey Abella, 16 Sep 2020
The final results of EVAPORATE* reinforce the plaque-regressing potential of icosapent ethyl (IPE) in patients on statins for elevated triglycerides.
01 Feb 2020
High-intensity statin therapy appears to be seeing increased use in patients with acute coronary syndrome and leads to better lipid control, according to a recent Thailand study.

Erectile dysfunction a potential marker of venous thromboembolism risk

05 Apr 2019

The risk of venous thromboembolism (VTE) in men appears to be elevated in the presence of erectile dysfunction (ED), a study has reported.

Researchers looked at 27,771 men participating in the Health Professionals Follow-up Study (HPFS) who had no VTE and prostate cancer at baseline. All participants completed biennial mailed questionnaires to report their current erectile function, which was categorized as ED presence (very poor or poor erectile function) or ED absence (fair, good or very good). Self-reported incident VTE included the first occurrence of either pulmonary embolism (PE) or deep vein thrombosis (DVT).

The average age of the cohort was 65 years, and 31 percent of men reported ED presence. A total of 665 VTE events occurred over 256,678 person-years of follow-up.

In multivariable Cox proportional hazards models, ED presence was associated with a 30-percent increase in the risk of developing VTE (adjusted hazard ratio [HR], 1.3; 95 percent CI, 1.1–1.6; erectile function linear ptrend=0.003).

Results were similar in a subgroup analysis limited to men with confirmed PE (n=196; PEs confirmed by medical record review/participant reconfirmation or self-reported among persons with prior cancer; adjusted HR, 1.3; 0.9–1.8).

Analyses were adjusted for traditional cardiovascular risk factors including age, smoking, body mass index, physical activity, caloric intake, race, alcohol consumption, aspirin use, diabetes, hypertension, hypercholesterolemia, myocardial infarction/angina, and cancer.

The present data indicate that ED presence may signal a higher risk of VTE, researchers said. Erectile function requires both intact arterial inflow and venous occlusion, and it has thus been suggested that ED could be a marker of cardiovascular risk.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.
Pearl Toh, 12 Sep 2020
Early initiation of rhythm-control therapy led to a significantly reduced risk of major adverse cardiovascular (CV) outcomes compared with usual care (typically rate control) in patients with newly diagnosed atrial fibrillation (AF) at risk of stroke, reveals the EAST-AFNET 4* trial presented at ESC 2020.
Audrey Abella, 16 Sep 2020
The final results of EVAPORATE* reinforce the plaque-regressing potential of icosapent ethyl (IPE) in patients on statins for elevated triglycerides.
01 Feb 2020
High-intensity statin therapy appears to be seeing increased use in patients with acute coronary syndrome and leads to better lipid control, according to a recent Thailand study.