Most Read Articles
Stephen Padilla, 4 days ago
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
14 May 2020
Webcast: Covid-19: What it means to your clinic. Practice pearls for the Asian primary care physician.
Roshini Claire Anthony, 08 May 2020

At present, there are no definitive treatments for COVID-19. More than 300 clinical trials are ongoing in the search for a cure. Some of the treatments being tested were previously used, with varying levels of efficacy, in the treatment of severe acute respiratory syndrome (SARS) or Middle East respiratory syndrome (MERS).

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Eosinophil count <2 percent predicts longer hospital stay in COPD exacerbations

26 Feb 2020

A blood eosinophil value of <0.144 × 109/L on admission or <2 percent is predictive of a longer hospital length of stay (LOS) among patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD), suggests a study.

The analysis included 346 patients with admission eosinophil count (mean age, 74.9±7.8 years; 96.2 percent males; mean forced expiratory volume in 1 s [FEV1], 43.4±16.3 percent predicted). The median of the absolute peripheral eosinophil count and percent eosinophil count was 0.11 × 109/L and 1 percent, respectively. The median LOS was 5 days.

Using the median LOS of ≥5 days as the cutoff, receiver operating characteristic (ROC) analysis revealed that a cutoff value of <2 percent eosinophil count (area under the curve [AUC], 0.666; p<0.001) correlated with longer LOS. The absolute eosinophil count stood at <0.144 × 109/L (AUC, 0.645; p<0.001).

“These eosinophil cutoff values could predict longer LOS independent of age, lung function and previous hospital admissions, but had no association with readmissions for AECOPD and mortality at 12 months,” the authors said.

This study recruited patients who presented to the hospital with an AECOPD, whose complete blood picture with differential count was taken upon admission. Participants received a standard course of systemic corticosteroid and antibiotic treatment. They were then evaluated at 8 weeks postexacerbation for lung function and 6-min walk.

The authors followed the patients up to 1 year for any readmissions or mortality. They used ROC curve analysis to calculate the cutoff values of eosinophils for the assessment of longer LOS.

“Airway inflammation accompanying exacerbations varies among individuals with some having neutrophilic, while others showing eosinophilic inflammation,” the authors noted.

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Most Read Articles
Stephen Padilla, 4 days ago
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
14 May 2020
Webcast: Covid-19: What it means to your clinic. Practice pearls for the Asian primary care physician.
Roshini Claire Anthony, 08 May 2020

At present, there are no definitive treatments for COVID-19. More than 300 clinical trials are ongoing in the search for a cure. Some of the treatments being tested were previously used, with varying levels of efficacy, in the treatment of severe acute respiratory syndrome (SARS) or Middle East respiratory syndrome (MERS).

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.