Most Read Articles
6 days ago
Electroretinogram-assessed localized retinal dysfunction in type 1 diabetes mellitus patients appears to occur even in the absence of clinical signs of diabetic retinopathy (DR), and this incidence is associated with ageing, according to a study.
Roshini Claire Anthony, 18 hours ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 3 days ago
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
6 days ago
Greater home blood pressure (BP) variability, particularly in home systolic (S)BP, correlates with higher carotid, aortic and peripheral but not coronary atherosclerosis burdens independent of the mean home BP, suggests a recent study.

Endobronchial valve treatment more cost-effective vs standard medical care in severe emphysema

06 Sep 2018

Use of endobronchial valves (EBV) is effective in the treatment of severe emphysema in patients without interlobar collateral ventilation, and these positive clinical effects correlated with increased costs compared with standard medical care (SoC), suggests a recent study.

Researchers performed an economic evaluation including the costs and cost-effectiveness of EBV treatment vs SoC from the hospital perspective in the short and long terms. For the short-term assessment, incremental cost-effectiveness ratios (ICER) were calculated based on the 6-month endpoint data from the STELVIO randomized trial. For the long-term evaluation, a Markov simulation model was generated based on STELVIO and literature.

Clinical outcome data were as follows: quality-adjusted life-years (QALY) based on the EuroQoL5-Dimensions (EQSD) questionnaire, the 6-min walking distance (6MWD) and the St George’s Respiratory Questionnaire (SGRQ).

There was a mean difference of €16,721/patient between the RBV group and controls. In the short term (6 months), costs per additional QALY was €205,129, and the corresponding ICER for 6MWD and for SGRQ were €160 and €1,241.

In the long term, the resulting cost-effectiveness ratios show additional costs of €39,000 and €21,500 per QALY gained with a 5- and 10-year time horizon, respectively. On the other hand, historical costs per additional QALY 1 year after the coil treatment are €738,400. Furthermore, the corresponding costs 5 years after lung volume reduction surgery and 15 years after double-lung transplantation are €48,415 and €29,410.

“Our results suggest that the EBV treatment has a favourable cost‐effectiveness profile, also when compared with other treatment modalities for this patient group,” the authors said.

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Most Read Articles
6 days ago
Electroretinogram-assessed localized retinal dysfunction in type 1 diabetes mellitus patients appears to occur even in the absence of clinical signs of diabetic retinopathy (DR), and this incidence is associated with ageing, according to a study.
Roshini Claire Anthony, 18 hours ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 3 days ago
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
6 days ago
Greater home blood pressure (BP) variability, particularly in home systolic (S)BP, correlates with higher carotid, aortic and peripheral but not coronary atherosclerosis burdens independent of the mean home BP, suggests a recent study.