Most Read Articles
Roshini Claire Anthony, 4 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
3 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.
4 days ago
There appears to be no clear link between pornography use, even at problematic levels, and erectile dysfunction, a recent US study has shown.

Endobronchial valve treatment more cost-effective vs standard medical care in severe emphysema

06 Sep 2018

Use of endobronchial valves (EBV) is effective in the treatment of severe emphysema in patients without interlobar collateral ventilation, and these positive clinical effects correlated with increased costs compared with standard medical care (SoC), suggests a recent study.

Researchers performed an economic evaluation including the costs and cost-effectiveness of EBV treatment vs SoC from the hospital perspective in the short and long terms. For the short-term assessment, incremental cost-effectiveness ratios (ICER) were calculated based on the 6-month endpoint data from the STELVIO randomized trial. For the long-term evaluation, a Markov simulation model was generated based on STELVIO and literature.

Clinical outcome data were as follows: quality-adjusted life-years (QALY) based on the EuroQoL5-Dimensions (EQSD) questionnaire, the 6-min walking distance (6MWD) and the St George’s Respiratory Questionnaire (SGRQ).

There was a mean difference of €16,721/patient between the RBV group and controls. In the short term (6 months), costs per additional QALY was €205,129, and the corresponding ICER for 6MWD and for SGRQ were €160 and €1,241.

In the long term, the resulting cost-effectiveness ratios show additional costs of €39,000 and €21,500 per QALY gained with a 5- and 10-year time horizon, respectively. On the other hand, historical costs per additional QALY 1 year after the coil treatment are €738,400. Furthermore, the corresponding costs 5 years after lung volume reduction surgery and 15 years after double-lung transplantation are €48,415 and €29,410.

“Our results suggest that the EBV treatment has a favourable cost‐effectiveness profile, also when compared with other treatment modalities for this patient group,” the authors said.

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Most Read Articles
Roshini Claire Anthony, 4 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
3 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.
4 days ago
There appears to be no clear link between pornography use, even at problematic levels, and erectile dysfunction, a recent US study has shown.