Most Read Articles
5 days ago
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Pearl Toh, 22 Oct 2020
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Jairia Dela Cruz, 4 days ago
The selective serotonin reuptake inhibitor escitalopram holds promise in the prevention of Alzheimer’s disease, reducing amyloid-β-42 levels in cerebrospinal fluid and brain tissue in older adults with normal cognitive function, according to recent evidence.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Elective C-section birth implicated in childhood obesity

16 Oct 2020

Kids delivered via elective, but not unplanned, caesarean section are at increased risk of developing obesity during preadolescent period, as suggested in a study.

The study used data from the WHEALS birth cohort and included 570 maternal–child pairs. There were 212 children (37.2 percent) born via C-section; 97 (54.2 percent) of these deliveries were unplanned, while 82 (45.8 percent) were planned.

At 10 years of age, 33 (5.8 percent) children were underweight, 339 (59.5 percent) had normal weight, 82 (14.4 percent) were overweight, and 116 (20.3 percent) were obese.

In multivariable logistic regression model, the odds of having obesity (body mass index ≥95th percentile) at 10 years of age were 77 percent greater among children born via planned C-section than among those delivered vaginally (risk ratio [RR], 1.77, 95 percent confidence interval [CI], 1.16–2.72; p=0.009). This association was not seen for unplanned C-section (RR, 0.75, 95 percent CI, 0.45–1.23; p=0.25).

Results were similar but slightly stronger when obesity was defined by anthropometric class (RR, 2.78, 95 percent CI, 1.47–5.26; p=0.002). Breastfeeding did not mediate the association between mode of delivery and obesity.

The present data suggest that partial labour or membrane rupture (typically experienced during unplanned C-section delivery) may be protective against the risk of childhood obesity, the researchers said. More studies are needed to shed light on the biological mechanisms behind the effect of mode of delivery on childhood obesity, whether microbiological differences fully or partially account for such.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
5 days ago
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Pearl Toh, 22 Oct 2020
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Jairia Dela Cruz, 4 days ago
The selective serotonin reuptake inhibitor escitalopram holds promise in the prevention of Alzheimer’s disease, reducing amyloid-β-42 levels in cerebrospinal fluid and brain tissue in older adults with normal cognitive function, according to recent evidence.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.