Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
3 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.

Elderly myocardial infarction patients benefit from 2 years of statins

12 Nov 2019

The use of statins is beneficial in elderly patients after their first myocardial infarction (MI) episode, particularly if medication is sustained for at least 2 years, a recent study has shown.

Researchers retrospectively assessed 9,020 elderly patients (aged 65 years) who had had their first MI episode. The primary outcome of interest was a composite between recurrent MI, cardiovascular mortality and stroke, whose occurrence was evaluated according to statin medication status. All-cause mortality was a secondary outcome.

Statin medication lasting >2 years reduced the incidence of the primary endpoint as compared to no statins in the 80-year age subgroup (adjusted hazard ratio [HR], 0.79, 95 percent confidence interval [CI], 0.62–1.02). This effect was statistically significant in participants aged 65–80 years (adjusted HR, 0.62, 95 percent CI, 0.44–0.88).

Prescriptions lasting 1–2 years, on the other hand, had no such effect in both the older and younger age subgroups (adjusted HR, 0.98, 95 percent CI, 0.75–1.29 and adjusted HR, 0.72, 95 percent CI, 0.49–1.05, respectively).

Interestingly, a statin regimen administered for less than a year yielded significant benefits for those aged 65–80 years (adjusted HR, 0.80, 95 percent CI, 0.67–0.95) and 80 years (adjusted HR, 0.51, 0.41–0.65).

Two- and <1-year courses of statin medication similarly improved all-cause mortality rates in both the older and younger age subgroups. Regimens lasting 1–2 years were not effective.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
3 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.