Most Read Articles
Pearl Toh, 07 Aug 2018
A home-based, self-applied wearable electrocardiogram (ECG) patch facilitates diagnosis of atrial fibrillation (AF) among high-risk individuals, according to the mSToPS* trial.
Roshini Claire Anthony, 3 days ago

A genotype-guided approach to warfarin dosing may result in fewer dose adjustments in Asian patients, according to a study from Singapore.

6 days ago

Fungal microbiome, also called the mycobiome, appears to be highly variable in patients with well-characterized fungal diseases, a recent study has shown. Moreover, severe asthmatics have the highest fungal loads, along with those receiving steroid and antifungal therapy.

Tristan Manalac, 4 days ago
The risk of complicated appendicitis is lower in children with IgE-mediated allergy, according to a recent study.

Elderly adults more likely to die from S. aureus bacteraemia

09 Aug 2018
Scientists have found a way to kill MRSA, the superior version of Staphylococcus aureus.

Advanced age, septic shock and liver cirrhosis increase the risk of mortality in adults with Staphylococcus aureus bacteraemia (SAB), a recent study has shown.

The 4-year retrospective observational study included 337 patients with SAB, of whom 35 percent (n=118) were aged >75 years. Clinical outcomes were compared between participants <75 vs 75 years. Multiple logistic regression analysis was performed to determine risk factors correlated with 7-day and 30-day hospital mortality.

Mortality by days 7 (20.3 percent vs 9.2 percent; p=0.004) and 30 (35.7 percent vs 20.7 percent; p=0.003) were significantly higher in the elderly vs younger adults. In the elderly adult group, septic shock was a risk factor for both 7-day (odds ratio [OR], 8.8; 95 percent CI, 2.7–32; p<0.001) and 30-day (OR, 2.7; 0.9–8.1) mortality.

In comparison, cirrhosis (OR, 8.4; 1.3–75.6; p=0.03) increased the likelihood of 7-day mortality, while adequate ab initio significantly reduced said risk (OR, 0.3; 0.1–0.9; p=0.03). Consultations for infectious diseases significantly reduced the risk of 30-day mortality in elderly adults (OR, 0.3; 0.1–0.7; p=0.006).

Notably, infection with methicillin-resistant S. aureus (MRSA) significantly increased the risk of 30-day mortality (OR, 2.4; 1.0–5.7; p=0.04). Such infections were reported in 39.2 percent (n=132) of the study sample and were equally distributed between the two age groups, though the elderly adults received empirical anti-MRSA treatment with significantly less frequency (15.0 percent vs 36.2 percent; p<0.001).

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Most Read Articles
Pearl Toh, 07 Aug 2018
A home-based, self-applied wearable electrocardiogram (ECG) patch facilitates diagnosis of atrial fibrillation (AF) among high-risk individuals, according to the mSToPS* trial.
Roshini Claire Anthony, 3 days ago

A genotype-guided approach to warfarin dosing may result in fewer dose adjustments in Asian patients, according to a study from Singapore.

6 days ago

Fungal microbiome, also called the mycobiome, appears to be highly variable in patients with well-characterized fungal diseases, a recent study has shown. Moreover, severe asthmatics have the highest fungal loads, along with those receiving steroid and antifungal therapy.

Tristan Manalac, 4 days ago
The risk of complicated appendicitis is lower in children with IgE-mediated allergy, according to a recent study.