Most Read Articles
5 days ago
Use of statin appears to reduce the risks of osteoporosis, hip fractures and vertebral fracture in patients newly diagnosed with a stroke, suggests a recent study.
2 days ago
Elderly adults using hypoglycaemic glucose-lowering drugs, such as insulin and glinides, have an excess risk of hospitalization for serious trauma, a recent study has found.
07 Oct 2018
Patients using long-acting opioids with immunosuppressive properties are at greater risk of developing serious infections compared with those using the nonimmunosuppressive opioid counterpart, according to a study.
6 days ago
Monitoring of adverse events is lower in ambulatory patients on amiodarone than in those on dofetilide, a recent study has found. Improving the monitoring of such agents may help reduce the risk of morbidity in this population.

Elderly adults more likely to die from S. aureus bacteraemia

09 Aug 2018
Scientists have found a way to kill MRSA, the superior version of Staphylococcus aureus.

Advanced age, septic shock and liver cirrhosis increase the risk of mortality in adults with Staphylococcus aureus bacteraemia (SAB), a recent study has shown.

The 4-year retrospective observational study included 337 patients with SAB, of whom 35 percent (n=118) were aged >75 years. Clinical outcomes were compared between participants <75 vs 75 years. Multiple logistic regression analysis was performed to determine risk factors correlated with 7-day and 30-day hospital mortality.

Mortality by days 7 (20.3 percent vs 9.2 percent; p=0.004) and 30 (35.7 percent vs 20.7 percent; p=0.003) were significantly higher in the elderly vs younger adults. In the elderly adult group, septic shock was a risk factor for both 7-day (odds ratio [OR], 8.8; 95 percent CI, 2.7–32; p<0.001) and 30-day (OR, 2.7; 0.9–8.1) mortality.

In comparison, cirrhosis (OR, 8.4; 1.3–75.6; p=0.03) increased the likelihood of 7-day mortality, while adequate ab initio significantly reduced said risk (OR, 0.3; 0.1–0.9; p=0.03). Consultations for infectious diseases significantly reduced the risk of 30-day mortality in elderly adults (OR, 0.3; 0.1–0.7; p=0.006).

Notably, infection with methicillin-resistant S. aureus (MRSA) significantly increased the risk of 30-day mortality (OR, 2.4; 1.0–5.7; p=0.04). Such infections were reported in 39.2 percent (n=132) of the study sample and were equally distributed between the two age groups, though the elderly adults received empirical anti-MRSA treatment with significantly less frequency (15.0 percent vs 36.2 percent; p<0.001).

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Most Read Articles
5 days ago
Use of statin appears to reduce the risks of osteoporosis, hip fractures and vertebral fracture in patients newly diagnosed with a stroke, suggests a recent study.
2 days ago
Elderly adults using hypoglycaemic glucose-lowering drugs, such as insulin and glinides, have an excess risk of hospitalization for serious trauma, a recent study has found.
07 Oct 2018
Patients using long-acting opioids with immunosuppressive properties are at greater risk of developing serious infections compared with those using the nonimmunosuppressive opioid counterpart, according to a study.
6 days ago
Monitoring of adverse events is lower in ambulatory patients on amiodarone than in those on dofetilide, a recent study has found. Improving the monitoring of such agents may help reduce the risk of morbidity in this population.