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Eating right boosts breast cancer survival

16 Sep 2020

Following an anti-inflammatory approach to diet following breast cancer diagnosis helps improves the outlook of patients, with its protective effects increasing over the long term, a study reports.

The analysis included 1,064 female breast cancer survivors in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening (PLCO) Trial prospective cohort, all of whom had completed the diet history questionnaire (DHQ).

Researchers calculated energy-adjusted dietary inflammatory index (E-DII) scores based on food and supplement intake, with higher scores indicating more pro-inflammatory diets and lower (ie, more negative) scores indicating more anti-inflammatory diets.

At baseline, patients consuming the most pro-inflammatory diets (ie, −4.1 to 4.9, E-DII tertile 3) had a higher total energy intake, higher body mass index, and more current hormone therapy, among others.

Over a median follow-up of 14.6 years, 296 (27.8 percent) all-cause and 100 (9.4 percent) breast cancer-specific deaths were recorded. Cox regression analysis revealed that consuming the most pro-inflammatory diets conferred increased risks of all-cause mortality (E-DII scores tertile 3 vs 1: hazard ratio [HR], 1.34, 95 percent confidence interval [CI], 1.01–1.81; ptrend=0.049) and breast cancer mortality (tertile 3 vs 1: HR, 1.47, 95 percent CI, 0.89–2.43; ptrend=0.13).

Each 1-unit increment in E-DII score was associated with a 6-percent increase in all-cause mortality risk (HR, 1.06, 95 percent CI, 1.00–1.13) and a 10-percent increase in breast cancer mortality (HR, 1.10, 95 percent CI, 1.00–1.22).

The findings highlight the potential of adopting anti-inflammatory diets after diagnosis as a means for reducing risk of breast cancer-specific and all-causes death among survivors, the researchers said.

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Most Read Articles
5 days ago
Ivermectin confers benefits in the treatment of COVID-19, with a recent study showing that its use helps reduce the risk of death especially in patients with severe pulmonary involvement.
4 days ago
Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Yesterday
Vitamin D deficiency may be a contributing factor to the mortality rate among patients with the novel coronavirus disease (COVID-19), reports a new study.