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Eating peanuts instead of rice bars as snacks improves MetS risk in adults

5 days ago

Replacing a refined-grain snack with peanuts in the habitual diet does not significantly change glycaemic or lipid parameters but improves overall metabolic syndrome (MetS) risk without inducing weight gain among adults at high risk of cardiometabolic diseases, according to a China study.

“Observational studies have suggested that intake of nuts is associated with lower risk of cardiometabolic diseases, whereas refined grain consumption has been linked to higher risk,” the authors said.

This parallel-arm randomized controlled trial sought to assess isocaloric substitution of peanuts for white rice bars as snacks on changes in fasting glucose, lipid profile, body weight, and changes in MetS status in Chinese adults.

A total of 224 participants either with MetS (according to the International Diabetes Federation criteria for Chinese adults; n=163) or at risk of MetS (central obesity plus 1 additional MetS risk factor; n=61) were included. They were then randomized to either the peanut arm (56 g/d as snacks; n=113) or the control arm (isocaloric white rice bars; n=111) for 12 weeks.

Of the participants, 209 (93.3 percent) completed the 12-week intervention with a compliance rate >85 percent. There were no between-group differences for improvements in fasting glucose, high-density lipoprotein cholesterol, waist circumference, and body weight.

The MetS reversion rate (no longer meeting the MetS criteria after the 12-week trial) was significantly higher among participants in the peanut group than those in the control group (relative risk, 2.33, 95 percent confidence interval, 1.10–4.89; p=0.026).

“Further larger-scale trials are needed to confirm these findings and elucidate underlying biological mechanisms,” the authors said.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
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