Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Early puberty onset in females predicts depression, antisocial behaviours in adulthood

13 Jan 2018

Early onset of puberty in young females results in higher rates of antisocial behaviour and depression, which persist into adulthood, a recent study has found.

The study included 7,802 females who were assessed for depressive symptoms and antisocial behaviours using self-reported questionnaires administered over five follow-up waves. Ordinary least-squares regression models were used to determine the relationship between the mental health symptoms and age at menarche.

According to the proximal influences model, early puberty onset was significantly and linearly predictive of depressive symptoms. That is, later ages of menarche were significantly correlated with lower symptom levels (p<0.05).

The researchers also found a borderline significant quadratic association between the two variables (p=0.09), indicating that earlier menarche may have compounding effects on later depressive symptoms.

Notably, the lingering influences model showed that earlier age of menarche was significantly associated with depressive symptoms both linearly (p<0.05) and quadratically (p<0.05) at the final follow-up. This suggests that young women who mature earlier are significantly more prone to depressive symptoms later in adulthood.

The trends were similar for antisocial behaviours. The proximal influences model revealed a significant and linear association between early maturation and the frequency of antisocial behaviour (p<0.05).

This relationship remained significant longitudinally (p<0.05) and even after controlling for adolescent levels of antisocial behaviours.

“The current research suggests that the sequelae of earlier development are not transient growing pains but are predictive of difficulties and challenges that persist into adulthood,” the researchers said.

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Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.