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Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
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Early puberty onset in females predicts depression, antisocial behaviours in adulthood

3 days ago

Early onset of puberty in young females results in higher rates of antisocial behaviour and depression, which persist into adulthood, a recent study has found.

The study included 7,802 females who were assessed for depressive symptoms and antisocial behaviours using self-reported questionnaires administered over five follow-up waves. Ordinary least-squares regression models were used to determine the relationship between the mental health symptoms and age at menarche.

According to the proximal influences model, early puberty onset was significantly and linearly predictive of depressive symptoms. That is, later ages of menarche were significantly correlated with lower symptom levels (p<0.05).

The researchers also found a borderline significant quadratic association between the two variables (p=0.09), indicating that earlier menarche may have compounding effects on later depressive symptoms.

Notably, the lingering influences model showed that earlier age of menarche was significantly associated with depressive symptoms both linearly (p<0.05) and quadratically (p<0.05) at the final follow-up. This suggests that young women who mature earlier are significantly more prone to depressive symptoms later in adulthood.

The trends were similar for antisocial behaviours. The proximal influences model revealed a significant and linear association between early maturation and the frequency of antisocial behaviour (p<0.05).

This relationship remained significant longitudinally (p<0.05) and even after controlling for adolescent levels of antisocial behaviours.

“The current research suggests that the sequelae of earlier development are not transient growing pains but are predictive of difficulties and challenges that persist into adulthood,” the researchers said.

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Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.