Most Read Articles
18 Aug 2018
Despite the absence of a substance use problem, regular cannabis use is associated with psychosocial impairment among adolescents and young adults, a study suggests. On the other hand, regular users with cannabis use disorder appear to exhibit high psychiatric comorbidity and more severe psychosocial impairment.
07 Sep 2018
Children with Down syndrome appear to have an elevated risk of developing severe respiratory syncytial virus (RSV) infection, a study has found.
Jairia Dela Cruz, 01 Sep 2018
Tight glycaemic control does not yield significant short-term survival gains and risk reductions for infections when compared with a conventional glucose-lowering strategy in critically ill patients in the paediatric intensive care unit, according to a meta-analysis.
01 Oct 2018
Due to varying analyses and reporting methods, fever rates in studies substantially differ. As such, there is a need for standardized fever reporting to allow comparisons between studies, according to a recent investigation.

Early progressive feeding ups number of full enteral feeding days in extremely preterm infants

04 Apr 2018

Early progressive feeding is feasible and effective in increasing the number of full enteral feeding days in extremely preterm infants, suggests a recent study.

A total of 60 infants (median gestation age, 26 weeks; mean birth weight, 832 g) were included. The number of full enteral feeding days in the first month after birth differed between groups (median difference favouring the early feeding group: 2 days; 95 percent CI, 0–3 days; p=0.02). In addition, the use of parenteral nutrition (4 vs 8 days; p≤0.01) and the need for central venous access (9 vs 13 days; p≤0.01) decreased with early progressive feeding.

There was no between-group difference in the outcome of culture-proven sepsis (10 percent vs 27 percent; p=0.18), restricted growth (weight, length and head circumference <10th percentile) at 36-week postmenstrual age (25 percent vs 50 percent; p=0.07) and the composite outcome of necrotizing enterocolitis (NEC) or death (27 percent vs 20 percent; p=0.74).

This single-centre study randomized extremely preterm infants (≤28 weeks of gestation) born between September 2016 and June 2017 to receive either early progressive feeding without trophic feeding (early feeding group) or delayed progressive feeding after a 4-day course of trophic feeding (delayed feeding group). Treatment was allocated on or before feeding day 1.

The primary outcome was the number of full enteral feeding days in the first month after birth, and secondary outcomes included death, NEC, culture-proven sepsis, growth percentiles at 36-week postmenstrual age, use of parenteral nutrition and need for central venous access.

“Due to insufficient evidence, extremely preterm infants rarely receive early progressive feeding (small increments of feeding volumes between 1 and 4 days after birth),” researchers said. “We hypothesized that early progressive feeding increases the number of full enteral feeding days in the first month after birth.”

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Most Read Articles
18 Aug 2018
Despite the absence of a substance use problem, regular cannabis use is associated with psychosocial impairment among adolescents and young adults, a study suggests. On the other hand, regular users with cannabis use disorder appear to exhibit high psychiatric comorbidity and more severe psychosocial impairment.
07 Sep 2018
Children with Down syndrome appear to have an elevated risk of developing severe respiratory syncytial virus (RSV) infection, a study has found.
Jairia Dela Cruz, 01 Sep 2018
Tight glycaemic control does not yield significant short-term survival gains and risk reductions for infections when compared with a conventional glucose-lowering strategy in critically ill patients in the paediatric intensive care unit, according to a meta-analysis.
01 Oct 2018
Due to varying analyses and reporting methods, fever rates in studies substantially differ. As such, there is a need for standardized fever reporting to allow comparisons between studies, according to a recent investigation.